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乳糜泻中的锌营养

Zinc nutrition in celiac sprue.

作者信息

Solomons N W, Rosenberg I H, Sandstead H H

出版信息

Am J Clin Nutr. 1976 Apr;29(4):371-5. doi: 10.1093/ajcn/29.4.371.

DOI:10.1093/ajcn/29.4.371
PMID:1266787
Abstract

Zinc nutritional status was examined in 10 adult patients with biopsy-proven celiac disease; five of these patients were clinically well on gluten-free diets at the time of study. Plasma zinc and taste acuity were used as indices of zinc nutrition. Depression of plasma zinc and lowered taste discrimination were observed among the untreated patients, and some patients who were otherwise in clinical remission also had impaired zinc nutrition. With confirmation of plasma copper depression in patients with celiac sprue, these observations indicate that trace metal deficiency is another common nutritional complication of adult celiac disease.

摘要

对10例经活检证实为乳糜泻的成年患者进行了锌营养状况检查;其中5例患者在研究时采用无麸质饮食,临床状况良好。血浆锌和味觉敏锐度被用作锌营养指标。在未经治疗的患者中观察到血浆锌降低和味觉辨别能力下降,一些临床缓解的患者也存在锌营养受损的情况。鉴于乳糜泻患者血浆铜降低得到证实,这些观察结果表明,微量金属缺乏是成人乳糜泻另一种常见的营养并发症。

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引用本文的文献

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Micronutrient deficiencies in patients with celiac disease: A systematic review and meta-analysis.乳糜泻患者的微量营养素缺乏:一项系统评价和荟萃分析。
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2
Zinc Deficiency and Therapeutic Value of Zinc Supplementation in Pediatric Gastrointestinal Diseases.锌缺乏与锌补充在儿科胃肠疾病中的治疗价值。
Nutrients. 2023 Sep 22;15(19):4093. doi: 10.3390/nu15194093.
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Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders.
50岁以上男性的锌缺乏及其对前列腺疾病的影响。
Front Oncol. 2020 Aug 6;10:1293. doi: 10.3389/fonc.2020.01293. eCollection 2020.
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Zinc and gastrointestinal disease.锌与胃肠道疾病
World J Gastrointest Pathophysiol. 2014 Nov 15;5(4):496-513. doi: 10.4291/wjgp.v5.i4.496.
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Zinc in taste function : A critical review.锌在味觉功能中的作用:一项批判性综述。
Biol Trace Elem Res. 1984 Jun;6(3):263-80. doi: 10.1007/BF02917511.
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Drug-induced taste and smell disorders. Incidence, mechanisms and management related primarily to treatment of sensory receptor dysfunction.药物性味觉和嗅觉障碍。发病率、机制及管理,主要涉及感觉受体功能障碍的治疗。
Drug Saf. 1994 Nov;11(5):318-77. doi: 10.2165/00002018-199411050-00004.
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