Sutter V L
Am J Med Technol. 1976 Apr;42(4):111-4.
Antimicrobial therapy of anaerobic infections is usually predicted on the basis of known patterns of susceptibility of anaerobic bacteria to antimicrobial agents rather than on results of in vitro tests of individual isolates. Routine susceptibility testing of anaerobic bacteria is not recommended, but there are instances of serious infection, i.e., endocarditis, or specific infecting organisms, e.g., Bacteroides fragilis, when in vitro testing of the specific infecting organism is indicated. No standard method has yet been accepted. Methods presently recommended are agar dilution or broth dilution tests. Other methods currently being evaluated are agar (disc) diffusion, broth-disc, and simplified broth and agar dilution tests. The advantages and limitations of the various methods are discussed.
厌氧菌感染的抗菌治疗通常基于厌氧菌对抗菌药物已知的敏感性模式来预测，而非单个分离株的体外测试结果。不建议对厌氧菌进行常规药敏试验，但在出现严重感染（如心内膜炎）或特定感染病原体（如脆弱拟杆菌）的情况下，则需要对特定感染病原体进行体外测试。目前尚未有被认可的标准方法。目前推荐的方法是琼脂稀释法或肉汤稀释法。目前正在评估的其他方法有琼脂（纸片）扩散法、肉汤纸片法以及简化的肉汤和琼脂稀释法。文中讨论了各种方法的优缺点。
