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[瑞士小型反刍动物的流产:在两个产羔季节(1996 - 1998年)的调查,特别关注衣原体引起的流产]

[Abortion in small ruminants in Switzerland: investigations during two lambing seasons (1996-1998) with special regard to chlamydial abortions].

作者信息

Chanton-Greutmann H, Thoma R, Corboz L, Borel N, Pospischil A

机构信息

Institut für Veterinärpathologie, Universität Zürich.

出版信息

Schweiz Arch Tierheilkd. 2002 Sep;144(9):483-92. doi: 10.1024/0036-7281.144.9.483.

Abstract

Abortion cases of 144 goats und 86 sheep were investigated etiologically during 2 lambing seasons (1996/1997, 1997/1998). Macroscopic inspection of fetus and placenta was completed by histopathology and bacteriological isolation of agents. In addition, immunohistologically the following antigens were labeled in formalin-fixed and paraffin-embedded tissue sections: Toxoplasma gondii, Neospora caninum, Chlamydophila abortus (formerly Chlamydia psittaci serovar 1) and Border Disease Virus. From farms with abortions caused by Chlamydophila abortus specific data were recorded. In 75% of abortion cases in sheep and in 59% of cases in goats an etiologic diagnosis could be substantiated. Chlamydophila abortus is the most commonly involved agent in the etiology of caprine and ovine abortion (sheep 39%, goats 23%), followed by Toxoplasma gondii (sheep 19%, goats 15%) and Coxiella burnetti (sheep 1%, goats 10%). All other agents are of minor importance. An infectious cause of abortion based on histopathologic findings without isolation of agents was observed in sheep (10%) and goats (21%). Malformation occurred in sheep (2%) and goats (3%) and lesions suggestive for Vitamin E/Selenium deficiency were seen in goats only (2%).

摘要

在两个产羔季节(1996/1997年、1997/1998年)对144只山羊和86只绵羊的流产病例进行了病因调查。通过组织病理学和病原体细菌分离对胎儿和胎盘进行了宏观检查。此外,在福尔马林固定、石蜡包埋的组织切片中,采用免疫组织化学方法标记了以下抗原:弓形虫、新孢子虫、流产嗜衣原体(原鹦鹉热衣原体血清型1)和边界病病毒。记录了由流产嗜衣原体引起流产的养殖场的具体数据。在75%的绵羊流产病例和59%的山羊流产病例中,可以证实病因诊断。流产嗜衣原体是山羊和绵羊流产病因中最常见的病原体(绵羊39%,山羊23%),其次是弓形虫(绵羊19%,山羊15%)和贝氏柯克斯体(绵羊1%,山羊10%)。所有其他病原体的重要性较低。在绵羊(10%)和山羊(21%)中观察到基于组织病理学发现但未分离出病原体的流产感染病因。绵羊(2%)和山羊(3%)出现畸形,仅在山羊(2%)中发现提示维生素E/硒缺乏的病变。

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