Heidari S, Derakhshandeh Abdollah, Firouzi R, Ansari-Lari M, Masoudian M, Eraghi V
Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran.
Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Trop Anim Health Prod. 2018 Apr;50(4):779-785. doi: 10.1007/s11250-017-1494-2. Epub 2017 Dec 19.
Abortion in sheep and goats has become increasingly important worldwide because of the significant economic losses and potential zoonotic implication of commonly involved pathogens. Therefore, this cross-sectional study was conducted in southern Iran to detect the Chlamydophila abortus and Coxiella burnetii, as zoonotic pathogens, and Mycoplasma agalactiae, as a neglected abortifacient agent in small ruminants' aborted fetuses, by using polymerase chain reaction (PCR). From a total of 300 aborted fetuses (183 sheep and 117 goats), 46 samples (15.5%) were positive by PCR, 11% for C. abortus, 2% for C. burnetii, and 3% for M. agalactiae. Also, the association of suggested risk factors with abortion due to these bacterial agents was investigated using univariable and multivariable logistic regression. Results of the statistical analysis showed significant association of C. abortus with flock size (OR = 2.82, P = 0.014), season (P < 0.05), and the number of pregnancy in the aborted dam (OR = 2.5, P = 0.05). Our results indicated that C. abortus has a relatively substantial role in small ruminant abortions, and C. burnetii and M. agalactiae are likely important abortifacient agents in our region, too. Regarding veterinary and/or public health importance of these bacterial agents, more attention from veterinary and/or human health services and, maybe, a surveillance system for control and prevention of them are recommended.
由于常见病原体造成的重大经济损失以及潜在的人畜共患病影响，绵羊和山羊流产问题在全球范围内日益重要。因此，本横断面研究在伊朗南部开展，通过聚合酶链反应（PCR）检测流产胎儿中的人畜共患病原体流产嗜衣原体和贝氏考克斯氏体，以及作为小型反刍动物中一种被忽视的流产病原体的无乳支原体。在总共300例流产胎儿（183只绵羊和117只山羊）中，46份样本（15.5%）经PCR检测呈阳性，流产嗜衣原体阳性率为11%，贝氏考克斯氏体阳性率为2%，无乳支原体阳性率为3%。此外，还使用单变量和多变量逻辑回归研究了建议的风险因素与这些细菌病原体导致的流产之间的关联。统计分析结果显示，流产嗜衣原体与畜群规模（OR = 2.82，P = 0.014）、季节（P < 0.05）以及流产母羊的妊娠次数（OR = 2.5，P = 0.05）之间存在显著关联。我们的结果表明，流产嗜衣原体在小型反刍动物流产中发挥着相对重要的作用，贝氏考克斯氏体和无乳支原体在我们地区可能也是重要的流产病原体。鉴于这些细菌病原体在兽医和/或公共卫生方面的重要性，建议兽医和/或人类健康服务机构给予更多关注，并可能建立一个监测系统来控制和预防它们。
