Eivindson Martin V, Hamilton-Dutoit Stephen, Grønbaek Henning
Medicinsk Afdeling V, Arhus Kommunehospital, DK-8000 Arhus V.
Ugeskr Laeger. 2003 Mar 10;165(11):1118-20.
Non-alcoholic steatohepatitis (NASH) may develop in a subset of patients with non-alcoholic fatty liver disease (NAFLD). NASH is strongly associated to the metabolic syndrome with insulin resistance and obesity. NASH can progress to liver fibrosis, cirrhosis and chronic hepatic failure and eventual need for a liver transplantation. Three case stories are presented with characteristic clinical and histopathological changes.
非酒精性脂肪性肝炎(NASH)可能在一部分非酒精性脂肪性肝病(NAFLD)患者中发生。NASH与伴有胰岛素抵抗和肥胖的代谢综合征密切相关。NASH可进展为肝纤维化、肝硬化和慢性肝衰竭,并最终需要进行肝移植。本文介绍了三个具有典型临床和组织病理学变化的病例。