Moran J M, Scanlon P J, Nemickas R, Pifarré R
Ann Thorac Surg. 1976 Feb;21(2):107-13. doi: 10.1016/s0003-4975(10)64272-5.
We have operated on 62 consecutive patients for postinfarction ventricular aneurysm since coronary bypass grafting became available. Analysis of hemodynamic and angiographic data reveals that the prognosis of operation is favorable if mean pulmonary artery pressure is less than 45 mm Hg and cardiac index is greater than 2.0 L/min/m2; such factors as the preoperative New York Heart Association Functional Class, number of coronary grafts, aneurysm size, left ventricular end-diastolic pressure, and coronary score were not closely related to the outcome of operation. Hospital mortality was 6.5% (4 patients) and late mortality, with a mean follow-up of two years, was 11% (7 patients). The prognosis among survivors was good: 82% (46) achieved NYHA Class I or II status, whereas 87% (54) had been in Class III or IV preoperatively. Concomitant vein grafting with aneurysmectomy did not significantly enhance operative or late survival, nor did it add appreciably to the risk of operation. Long-term benefits of revascularization in addition to aneurysmectomy are expected but not yet proved.
自从能够进行冠状动脉搭桥手术以来,我们连续对62例心肌梗死后室壁瘤患者施行了手术。对血流动力学和血管造影数据的分析显示,如果平均肺动脉压低于45 mmHg且心脏指数大于2.0 L/min/m²,手术预后良好;术前纽约心脏协会心功能分级、冠状动脉搭桥数量、瘤体大小、左心室舒张末期压力和冠状动脉评分等因素与手术结果并无密切关系。医院死亡率为6.5%(4例患者),平均随访两年的晚期死亡率为11%(7例患者)。存活者的预后良好:82%(46例)达到纽约心脏协会心功能I级或II级状态,而术前87%(54例)处于III级或IV级。同时进行静脉搭桥和瘤体切除术并未显著提高手术或晚期生存率,也未明显增加手术风险。除瘤体切除外,血运重建的长期益处虽有预期但尚未得到证实。