Nemerofsky A
Can J Genet Cytol. 1975 Jun;17(2):275-8. doi: 10.1139/g75-036.
5-Bromouracil (5-BU) was shown to enhance reverse mutation rates when added to conidia of a rib-1 strain of Neurospora crassa previously irradiated with ultraviolet light. A comparison is presented between various incubation intervals in the presence and absence of 5-BU while varying the UV dose. An increase in mutation frequency ranging from 0.028 - 2.05 X 10(2) times greater than the spontaneous frequency, UV frequency alone or 5-BU frequency alone was observed when UV irradiation and 5-BU were combined.
当将5-溴尿嘧啶（5-BU）添加到先前经紫外线照射的粗糙脉孢菌rib-1菌株的分生孢子中时，它能提高回复突变率。本文比较了在存在和不存在5-BU的情况下，不同孵育时间间隔并改变紫外线剂量时的情况。当紫外线照射和5-BU联合使用时，观察到突变频率增加，比自发频率、单独的紫外线频率或单独的5-BU频率高出0.028 - 2.05×10²倍。
