Millns B, Gosney M, Jack C I A, Martin M V, Wright A E
Department of Dental Sciences, University of Liverpool, UK.
Gerontology. 2003 May-Jun;49(3):173-6. doi: 10.1159/000069171.
To assess any change in the oral flora in the mouths of stroke patients during the acute and rehabilitation phases and to determine whether this is related to episodes of aspiration pneumonia and clinical outcome.
This observational study was carried out in hospital wards in a University teaching hospital. The subjects were patients immediately post-stroke and during the rehabilitation period, acute admissions and a group of healthy volunteers. An assessment of dentition and swallow in the presence or absence of oral aerobic gram-negative bacilli (AGNB) was correlated.
Of the acute stroke patients 52% had an unsafe swallow. AGNB carriage was documented in 34% of the acute stroke group. Of the 11 patients who died 55% had AGNB, 73% had an unsafe swallow and 36% had a combination of both.
AGNB is a common finding in acute stroke patients. It is not a consequence of age or acute hospitalisation and is associated with an unsafe swallow and a higher mortality.
评估中风患者在急性期和康复期口腔菌群的任何变化，并确定这是否与吸入性肺炎发作及临床结局相关。
本观察性研究在一所大学教学医院的病房中进行。研究对象为刚发生中风的患者、康复期患者、急性入院患者以及一组健康志愿者。对存在或不存在口腔需氧革兰氏阴性杆菌（AGNB）情况下的牙列和吞咽情况进行评估并相互关联。
在急性中风患者中，52%存在吞咽不安全情况。急性中风组中有34%记录到携带AGNB。在11例死亡患者中，55%携带AGNB，73%存在吞咽不安全情况，36%两者兼有。
AGNB在急性中风患者中很常见。它不是年龄或急性住院的结果，并且与吞咽不安全及较高死亡率相关。
