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在微生物风险评估中纳入易感亚群:儿童接触河水中肠道病毒的情况。

Incorporating susceptible subpopulations in microbial risk assessment: pediatric exposures to enteroviruses in river water.

作者信息

Parkin Rebecca T, Soller Jeffrey A, Olivieri Adam W

机构信息

Center for Risk Science and Public Health, The George Washington University Medical Center, 2300 K Street, NW, Suite 201, Washington, DC 20037, USA.

出版信息

J Expo Anal Environ Epidemiol. 2003 Mar;13(2):161-8. doi: 10.1038/sj.jea.7500265.

Abstract

The City of Stockton, California operates a wastewater treatment facility that discharges treated effluent to the San Joaquin River. During a recent discharge permit renewal, the question was raised whether pathogenic microorganisms in the effluent may cause an unacceptably high health risk for body contact recreation in the vicinity of the discharge. An investigation was initiated to characterize the risk to public health via body contact recreation in the San Joaquin River under various flow and treatment scenarios. In this investigation, a disease transmission model was applied to quantitatively characterize the relative risk associated with various treatment and flow scenarios for the City of Stockton's wastewater treatment facility. An important component of the investigation was to assess the feasibility of quantitatively characterizing the risk to highly susceptible subpopulations for effluent-related exposures to enteroviruses. This paper presents the methods used to conduct the feasibility assessment, the conclusions drawn for this project, and our recommendations to improve exposure assessments of susceptible subpopulations' contact with microbial pathogens in recreational water.

摘要

加利福尼亚州斯托克顿市运营着一座废水处理设施,该设施将处理后的废水排放到圣华金河。在最近一次排放许可续期过程中,有人提出废水当中的病原微生物是否会给排放口附近的人体接触式娱乐活动带来高到无法接受的健康风险这一问题。于是展开了一项调查,以确定在各种流量和处理方案下,通过在圣华金河进行人体接触式娱乐活动对公众健康造成的风险特征。在本次调查中,应用了一种疾病传播模型来定量描述斯托克顿市废水处理设施在各种处理和流量方案下的相对风险。该调查的一个重要组成部分是评估定量描述高易感亚人群因接触与肠道病毒相关的废水而面临的风险的可行性。本文介绍了用于进行可行性评估的方法、该项目得出的结论,以及我们对改进易感亚人群接触娱乐用水中微生物病原体的暴露评估的建议。

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