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兰德里-古兰-巴雷-施特罗尔综合征中的视神经炎。

Optic neuritis in the Landry-Guillain-Barré-Strohl syndrome.

作者信息

Behan P O, Lessell S, Roche M

出版信息

Br J Ophthalmol. 1976 Jan;60(1):58-9. doi: 10.1136/bjo.60.1.58.

Abstract

A patient with typical Landry-Guillain-Barré-Strohl syndrome (LG-BS) developed bilateral optic neuritis. Laboratory studies showed hypersensitivity to both central and peripheral nervous tissue myelin. The occurrence of optic neuritis is presumably due to autohypersensitivity to central nervous tissue myelin. The initial lesions of the LG-BS syndrome in the peripheral nerves might have liberated sequestered antigens that cross-reacted with central nervous system myelin.

摘要

一名患有典型兰德里-吉兰-巴雷-施特罗尔综合征(LG-BS)的患者出现了双侧视神经炎。实验室研究显示对中枢和外周神经组织髓鞘均过敏。视神经炎的发生可能是由于对中枢神经组织髓鞘的自身过敏。LG-BS综合征在外周神经的初始病变可能释放了与中枢神经系统髓鞘发生交叉反应的隐蔽抗原。

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