氨苯蝶啶对心脏病患者白细胞钠钾水平的影响。
Effect of triamterene on leucocyte sodium and potassium levels in heart disease.
作者信息
Donaldson E K, Patrick J, Sivapragasm S, Ming M O, Alleyne G A
出版信息
Br Med J. 1976 May 22;1(6020):1254-5. doi: 10.1136/bmj.1.6020.1254.
Sodium and potassium levels in plasma and leucocytes and the sodium efflux rate constants of leucocytes were measured in patients with congenital heart disease not on treatment, patients with valvular heart disease being treated with digoxin and conventional diuretics, and patients with valvular heart disease receiving digoxin and either conventional diuretics or triamterene or both. The group being treated with digoxin and conventional diuretics showed low cellular potassium levels, low sodium efflux rate constants, and a rise in cellular sodium levels. Patients given triamterene showed a rise in potassium levels in plasma and cells and in the sodium efflux rate constant.
对未经治疗的先天性心脏病患者、正在接受地高辛和传统利尿剂治疗的瓣膜性心脏病患者，以及接受地高辛和传统利尿剂或氨苯蝶啶或两者联合治疗的瓣膜性心脏病患者，测量了血浆和白细胞中的钠和钾水平以及白细胞的钠流出速率常数。接受地高辛和传统利尿剂治疗的组显示细胞钾水平低、钠流出速率常数低以及细胞钠水平升高。给予氨苯蝶啶的患者血浆和细胞中的钾水平以及钠流出速率常数均升高。
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