Binette J P, Montes M
Can Med Assoc J. 1976 May 8;114(9):810-2.
A 19-year-old man presented with dyspnea, cough and chest pains; he also complained of nausea, anorexia and postprandial vomiting and reported a 10-kg weight loss. Generalized lymphadenopathy and some rales over both lung bases were noted and a chest radiograph showed bilateral nodular lesions. Persistent leukocytosis, thrombocytosis, proteinuria and anergy to a series of natural antigens were found. The diagnosis of lymphoid interstitial pneumonia was made from material obtained at open lung biopsy. Rapid but incomplete clearing of the lung lesions resulted from steroid therapy; the other abnormalities were corrected gradually, except for the proteinuria, which persisted. The clinical improvement and the ability to work and play have been maintained for the past 20 months.
一名19岁男性出现呼吸困难、咳嗽和胸痛；他还主诉恶心、厌食和餐后呕吐，并报告体重减轻了10公斤。发现全身淋巴结肿大以及双肺底部有一些啰音，胸部X线片显示双侧结节性病变。发现持续白细胞增多、血小板增多、蛋白尿以及对一系列天然抗原无反应。通过开胸肺活检获取的材料确诊为淋巴间质性肺炎。类固醇治疗使肺部病变迅速但未完全消退；其他异常逐渐得到纠正，但蛋白尿持续存在。在过去20个月里，临床症状得到改善，患者能够维持工作和娱乐。
