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急性心肌梗死后血清中的多巴胺-β-羟化酶活性:对该参数作为交感神经活动指标常规应用的评估。

Dopamine-beta-hydroxylase activity in serum following acute myocardial infarction: an evaluation of this parameter for routine use as an index of sympathetic activity.

作者信息

Gutteberg T, Borud O, Stromme J H

出版信息

Clin Chim Acta. 1976 May 17;69(1):61-6. doi: 10.1016/0009-8981(76)90471-x.

DOI:10.1016/0009-8981(76)90471-x
PMID:1269153
Abstract

Dopamine-beta-hydroxylase activity was measured in sera from 114 normal males and from 11 patients on the 1st, 2nd, 3rd, 5th and 10th day following acute myocardial infarction. A significant elevation of dopamine-beta-hydroxylase levels (P less than 0.001) was found during the first two days after infarction when compared with the 10th-day values. Only a few activities were above the reference range. Temporary elevations of glucose and glycerol levels were also found. Assay of serum dopamine-beta-hydroxylase may be a useful parameter of sympathetic activity in longitudinal studies in which each individual is used as his own reference.

摘要

在114名正常男性以及11例急性心肌梗死后第1、2、3、5和10天的患者血清中测量了多巴胺-β-羟化酶活性。与第10天的值相比,梗死后头两天发现多巴胺-β-羟化酶水平显著升高(P<0.001)。只有少数活性高于参考范围。还发现葡萄糖和甘油水平有暂时升高。血清多巴胺-β-羟化酶的测定可能是纵向研究中交感神经活动的一个有用参数,在这些研究中,每个个体都以自身作为对照。

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1
Dopamine-beta-hydroxylase activity in serum following acute myocardial infarction: an evaluation of this parameter for routine use as an index of sympathetic activity.急性心肌梗死后血清中的多巴胺-β-羟化酶活性:对该参数作为交感神经活动指标常规应用的评估。
Clin Chim Acta. 1976 May 17;69(1):61-6. doi: 10.1016/0009-8981(76)90471-x.
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Serum dopamine beta-hydroxylase (DBH) activity in acute myocardial infarction.急性心肌梗死时的血清多巴胺β-羟化酶(DBH)活性
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Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activity in myocardial infarction with and without cardiogenic shock.伴有和不伴有心源性休克的心肌梗死患者的血浆肾上腺素、去甲肾上腺素浓度及多巴胺-β-羟化酶活性
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引用本文的文献

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Changes in plasma dopamine-beta-hydroxylase activity during the perioperative period of cardiac surgery: an index of sympathetic nerve activity.
Surg Today. 1993;23(7):587-91. doi: 10.1007/BF00311905.
2
Dopamine-beta-hydroxylase in patients with cystic fibrosis.囊性纤维化患者体内的多巴胺-β-羟化酶
Eur J Pediatr. 1986 Apr;145(1-2):80-3. doi: 10.1007/BF00441861.
3
Intravenous atenolol in elderly patients in the early phase of acute myocardial infarction.急性心肌梗死早期老年患者静脉注射阿替洛尔
Cardiovasc Drugs Ther. 1992 Oct;6(5):475-9. doi: 10.1007/BF00055604.
4
Changes of dopamine beta-hydroxylase activity in human plasma during prolonged overactivity of the sympathetic nervous system in various diseases.在各种疾病中交感神经系统长期过度活跃期间人血浆中多巴胺β-羟化酶活性的变化。
Naunyn Schmiedebergs Arch Pharmacol. 1978 Jul;303(3):235-42. doi: 10.1007/BF00498049.
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Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activity in myocardial infarction with and without cardiogenic shock.伴有和不伴有心源性休克的心肌梗死患者的血浆肾上腺素、去甲肾上腺素浓度及多巴胺-β-羟化酶活性
Br Heart J. 1979 Aug;42(2):214-20. doi: 10.1136/hrt.42.2.214.