伴有和不伴有心源性休克的心肌梗死患者的血浆肾上腺素、去甲肾上腺素浓度及多巴胺-β-羟化酶活性
Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activity in myocardial infarction with and without cardiogenic shock.
作者信息
Benedict C R, Grahame-Smith D G
出版信息
Br Heart J. 1979 Aug;42(2):214-20. doi: 10.1136/hrt.42.2.214.
Abstract
In patients with myocardial infarction, with or without cardiogenic shock, plasma noradrenaline and adrenaline concentrations are increased. However, plasma noradrenaline concentrations are considerably higher in patients with cardiogenic shock when compared with those with uncomplicated myocardial infarction. Plasma noradrenaline and adrenaline concentrations showed a sustained increase until death in patients with cardiogenic shock whereas those concentrations were back to normal levels by the end of the third day in patients with uncomplicated myocardial infarction. Plasma dopamine-beta-hydroxylase activities in both the groups were within normal range and did not show any significant variation throughout the period of study.
摘要
在心肌梗死患者中，无论有无心源性休克，血浆去甲肾上腺素和肾上腺素浓度都会升高。然而，与无并发症的心肌梗死患者相比，心源性休克患者的血浆去甲肾上腺素浓度要高得多。心源性休克患者的血浆去甲肾上腺素和肾上腺素浓度持续升高直至死亡，而无并发症的心肌梗死患者在第三天结束时这些浓度恢复到正常水平。两组患者的血浆多巴胺-β-羟化酶活性均在正常范围内，且在整个研究期间未显示出任何显著变化。
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