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急性心肌梗死时的血清多巴胺β-羟化酶(DBH)活性

Serum dopamine beta-hydroxylase (DBH) activity in acute myocardial infarction.

作者信息

Nicolosi G L, Atkins F

出版信息

Clin Chim Acta. 1978 Dec 15;90(3):279-84. doi: 10.1016/0009-8981(78)90267-x.

DOI:10.1016/0009-8981(78)90267-x
PMID:729170
Abstract

Serial serum dopamine beta-hydroxylase (DBH) activities were determined in 32 patients admitted to the Coronary Care Unit with chest pain, 9 with acute myocardial infarction and 23 with other diagnoses. The values of DBH were elevated in both groups on day one. The acute myocardial infarction group showed a slower decline and reached a baseline plateau at day five when compared to the control group whose values fell significantly by day two. The reason for the quantitative difference between the two groups is speculative and may be related to changes in plasma volume. Increases in DBH are not specific for myocardial infarction but a nonspecific responses to stress.

摘要

对32名因胸痛入住冠心病监护病房的患者、9名急性心肌梗死患者和23名其他诊断患者进行了血清多巴胺β-羟化酶(DBH)活性的连续测定。两组患者在第一天时DBH值均升高。与对照组相比,急性心肌梗死组下降较慢,在第五天达到基线平稳期,而对照组的值在第二天就显著下降。两组之间定量差异的原因尚属推测,可能与血浆容量的变化有关。DBH升高并非心肌梗死所特有,而是对压力的非特异性反应。

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