Matsunaga Shinichi, Kurashima Atsuyuki, Nagai Hideaki, Akagawa Shinobu, Machida Kazuko, Yotsumoto Hideki, Mouri Masashi, Hebisawa Akira
Department of Respiratory Medicine, National Sanatorium Tokyo Hospital.
Nihon Kokyuki Gakkai Zasshi. 2003 Jan;41(1):14-8.
A 64-year-old man was admitted to our hospital because of productive cough and fever. Chest radiography on admission revealed air space consolidation in the right middle and lower lung fields and ground-glass opacity in the left middle lung field. He had been constipated for several years and had taken mineral oil for about a year. Sputum smears demonstrated acid bacilli, and cultures disclosed Mycobacterium abscessus. The transbronchial lung biopsy specimen showed granulomatous inflammation and numerous lipoid-laden macrophages in the alveolar spaces. Mycobacteria were present within the mineral oil and lipid-laden macrophages. It is likely that the mineral oil increased the pathogenicity of the mycobacteria.
一名64岁男性因咳痰和发热入住我院。入院时胸部X线检查显示右中、下肺野实变,左中肺野磨玻璃影。他便秘数年,服用矿物油约一年。痰涂片显示抗酸杆菌,培养发现脓肿分枝杆菌。经支气管肺活检标本显示肉芽肿性炎症,肺泡腔内有大量充满脂质的巨噬细胞。矿物油和充满脂质的巨噬细胞内存在分枝杆菌。很可能是矿物油增加了分枝杆菌的致病性。