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缺氧会增加哺乳动物心肌中的钾离子外流。

Hypoxia increases potassium efflux from mammalian myocardium.

作者信息

Vleugels A, Carmeliet E

出版信息

Experientia. 1976 Apr 15;32(4):483-4. doi: 10.1007/BF01920810.

DOI:10.1007/BF01920810
PMID:1269655
Abstract

Hypoxia with or without simultaneous depletion of extracellular glucose increases 42K-efflux in cat and guinea-pig papillary muscles and bovine Purkinje fibres. The change observed in K efflux may be the result of an increase in K conductance at rest.

摘要

伴有或不伴有细胞外葡萄糖同时耗竭的缺氧会增加猫和豚鼠乳头肌以及牛浦肯野纤维中的42K外流。观察到的钾外流变化可能是静息时钾电导增加的结果。

相似文献

1
Hypoxia increases potassium efflux from mammalian myocardium.缺氧会增加哺乳动物心肌中的钾离子外流。
Experientia. 1976 Apr 15;32(4):483-4. doi: 10.1007/BF01920810.
2
Reduction of potassium permeability by chloride substitution in cardiac cells.通过氯离子替代降低心脏细胞中的钾离子通透性。
J Physiol. 1977 Feb;265(1):193-206. doi: 10.1113/jphysiol.1977.sp011712.
3
Decrease of K efflux and influx by external Cs ions in cardiac Purkinje and muscle cells.心脏浦肯野细胞和肌肉细胞中外源性铯离子对钾离子外流和内流的减少作用。
Pflugers Arch. 1980 Jan;383(2):143-50. doi: 10.1007/BF00581875.
4
The correlation between action potential duration and 42K-efflux in the hypoxic myocardium.缺氧心肌中动作电位持续时间与42K外流之间的相关性。
Arch Int Physiol Biochim. 1976;84(3):547-8.
5
Metabolic depression and myocardial potassium.
Pflugers Arch. 1972;335(4):266-78. doi: 10.1007/BF00586217.
6
Effects of K+ and K+-induced polarization on (dV/dt)max, threshold potential, and membrane input resistance in guinea pig and cat ventricular myocardium.钾离子及钾离子诱导的极化对豚鼠和猫心室肌最大去极化速率、阈电位和膜输入电阻的影响。
Circ Res. 1979 Jun;44(6):800-14. doi: 10.1161/01.res.44.6.800.
7
Intracellular pH in sheep Purkinje fibres and ferret papillary muscles during hypoxia and recovery.绵羊浦肯野纤维和雪貂乳头肌在缺氧及恢复过程中的细胞内pH值
J Physiol. 1987 Feb;383:125-41. doi: 10.1113/jphysiol.1987.sp016400.
8
The role of the sodium pump in the effects of potassium-depleted solutions on mammalian cardiac muscle.钠泵在低钾溶液对哺乳动物心肌作用中的角色。
J Physiol. 1979 Sep;294:279-301. doi: 10.1113/jphysiol.1979.sp012930.
9
Cardiac transmembrane potentials and metabolism.心脏跨膜电位与代谢。
Circ Res. 1978 May;42(5):577-87. doi: 10.1161/01.res.42.5.577.
10
Potassium loss from rabbit myocardium during hypoxia: evidence for passive efflux linked to anion extrusion.缺氧期间兔心肌的钾离子丢失：与阴离子外排相关的被动外流证据。
J Mol Cell Cardiol. 1986 Apr;18(4):389-99. doi: 10.1016/s0022-2828(86)80902-6.

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Non-Mammalian Vertebrates: Distinct Models to Assess the Role of Ion Gradients in Energy Expenditure.非哺乳动物脊椎动物：评估离子梯度在能量消耗中作用的独特模型。
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3
Effects of hypoxia on passive electrical properties of canine ventricular muscle.缺氧对犬心室肌被动电特性的影响。

本文引用的文献

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Electrical activity and metabolism in cardiac tissue: An experimental and theoretical study.心肌组织的电活动和代谢：实验与理论研究。
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2
[Action potential and contraction of the myocardium in oxygen deficiency].[缺氧状态下心肌的动作电位与收缩]
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4
The shortening of the action potential by DNP in guinea-pig ventricular myocytes is mediated by an increase of a time-independent K conductance.二硝基酚（DNP）使豚鼠心室肌细胞动作电位缩短是由一种非时间依赖性钾电导增加介导的。
Pflugers Arch. 1983 Jun 1;397(4):251-9. doi: 10.1007/BF00580257.
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The influence of hypoxia and metabolic inhibitors on the excitation process in atrioventricular node.
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Basic Res Cardiol. 1987 Jan-Feb;82(1):74-81. doi: 10.1007/BF01907055.
7
Conduction of the impulse in the ischemic myocardium--implications for malignant ventricular arrhythmias.缺血心肌中的冲动传导——对恶性室性心律失常的影响
Experientia. 1987 Oct 15;43(10):1056-61. doi: 10.1007/BF01956039.
8
Effect of trimetazidine on membrane damage induced by oxygen free radicals in human red cells.曲美他嗪对人红细胞中氧自由基诱导的膜损伤的影响。
Br J Clin Pharmacol. 1985 Aug;20(2):148-51. doi: 10.1111/j.1365-2125.1985.tb05047.x.
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The pharmacology of ATP-sensitive K+ channels in the heart.
Pflugers Arch. 1989;414 Suppl 1:S93-8. doi: 10.1007/BF00582255.
10
Effects of anoxia on K and Ca currents in isolated guinea pig cardiocytes.缺氧对离体豚鼠心肌细胞钾电流和钙电流的影响。
Pflugers Arch. 1990 Apr;416(1-2):207-9. doi: 10.1007/BF00370244.
Pflugers Arch Gesamte Physiol Menschen Tiere. 1954;260(1):40-60. doi: 10.1007/BF00363778.
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Maintenance of resting potential in anoxic guinea pig ventricular muscle: electrogenic sodium pumping.
Science. 1971 May 7;172(3983):570-2. doi: 10.1126/science.172.3983.570.
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Dynamic energy partition in cultured heart cells.培养心肌细胞中的动态能量分配
Cardiology. 1971;56(1):88-92. doi: 10.1159/000169345.
6
The effect of 2,4-dinitrophenol on electrical and mechanical activity, metabolism and ion movements in guinea-pig ventricular muscle.2,4-二硝基苯酚对豚鼠心室肌电活动、机械活动、代谢及离子转运的影响
Br J Pharmacol. 1972 Apr;44(4):711-22. doi: 10.1111/j.1476-5381.1972.tb07309.x.
7
Anoxic atrial and ventricular muscle electrical activity, cell potassium, and metabolism: a comparative study.缺氧心房和心室肌电活动、细胞钾及代谢：一项比较研究。
J Mol Cell Cardiol. 1973 Apr;5(2):149-59. doi: 10.1016/0022-2828(73)90048-5.
8
Is potassium conductance of cardiac Purkinje fibres controlled by (Ca2+)?
Nature. 1975 Jan 24;253(5489):273-4. doi: 10.1038/253273a0.
9
Proceedings: Intracellula Na and K concentrations and membrane potential in chick embryonic heart under hypoxic conditions.论文：缺氧条件下鸡胚心脏细胞内钠、钾浓度及膜电位
Arch Int Physiol Biochim. 1975 Feb;83(1):148-50.