皮肤癣菌及其体外抗真菌敏感性研究。

A study of dermatophytes and their in-vitro antifungal sensitivity.

作者信息

Sumana M N, Rajagopal V

机构信息

Department of Microbiology, Govt. Medical College, Mysore.

出版信息

Indian J Pathol Microbiol. 2002 Apr;45(2):169-72.

PMID:12696733

Abstract

Of the 150 clinically suspected cases of Dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), Tinea corporis (48.7%) and Tinea capitis (18%) were the commonest clinical types. The isolation rate was 24% (36) of which 19 (52.7%) were Trichophyton rubrum, 11 (30.55%) were Trichophyton mentagrophytes and 4 (11.1%) were Trichophyton violaceum. One isolate each of Microsporum gypseum & Epidermophyton floccosum were obtained. Griseofulvin proved to be the best drug with a sensitivity of 94.4% followed by Miconazole (75% sensitive). Tolnaftate showed a sensitivity of 47.22%. For Clotrimazole only 30.55% of the isolates were sensitive.

摘要

在研究的150例临床疑似皮肤癣菌病病例中，大多数病例来自11 - 20岁和21 - 30岁年龄组（51.4%），体癣（48.7%）和头癣（18%）是最常见的临床类型。分离率为24%（36株），其中红色毛癣菌19株（52.7%），须癣毛癣菌11株（30.55%），紫色毛癣菌4株（11.1%）。还获得了1株石膏样小孢子菌和1株絮状表皮癣菌。灰黄霉素被证明是最佳药物，敏感性为94.4%，其次是咪康唑（75%敏感）。托萘酯的敏感性为47.22%。仅30.55%的分离株对克霉唑敏感。