[从正常人群到中风患者脑血管血流动力学的变化]

[Changes of cerebral vascular hemodynamics from normal population to stroke].

作者信息

Yang Bo-sheng, Wang Gui-qing, Wang Yan, Yu Xue-hai, Guo Ji-ping, Wang Su-chun, Yang Yong-ju

机构信息

Department of Neurology, Fuzhou General Hospital of The Chinese People's Liberalion Army, Fuzhou 350021, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Feb;24(2):94-7.

PMID:12697106

Abstract

OBJECTIVE

To probe into changes of cerebral vascular hemodynamics indexes (CVHI) from normal population to different clinical stage before and after occurring of stroke.

METHODS

Participants were selected from 25,355 stroke cohort study population aged 35 years and over in Northeast of China and 55 acute stroke patients were selected from Fuzhou PLA General Hospital. CVHI indexes were checked during baseline investigation or within one week after acute stroke. Participant enlisted in the study were divided into following 5 groups, normal population, high risk population, individuals before stroke, acute stroke patients and convalescence stroke patients. Characteristics of CVHI indexes in different population were analyzed and compared.

RESULTS

V(min) of cerebral vascular in previous defined 5 group participants were 11.39 +/- 3.27, 9.66 +/- 3.18, 6.71 +/- 3.30, 4.13 +/- 1.27, 6.78 +/- 3.09, respectively. V(mean) and V(max) were with the same decreasing trends as V(min). However, RV in 5 group participants were 62.35 +/- 21.11, 82.32 +/- 31.16, 122.72 +/- 52.73, 137.46 +/- 49.56 and 115.89 +/- 55.51, respectively. Zcv, WV, DR and CP were also with the same increasing trends as RV. Abnormal rate of CVHI score (< 75 points) from normal population to convalescence stroke patients were 13.3%, 34.7%, 74.1%, 100% and 66.7%, respectively.

CONCLUSION

From normal population to clinical stage of stroke, cerebral vascular velocity showed decreasing trends while other indexes, such as RV, Zcv, WV, DR and CP were increasing.

摘要

目的

探讨从正常人群到脑卒中发生前后不同临床阶段脑血管血流动力学指标（CVHI）的变化。

方法

从中国东北地区25355名35岁及以上的脑卒中队列研究人群中选取参与者，并从福州解放军总医院选取55例急性脑卒中患者。在基线调查期间或急性脑卒中后一周内检查CVHI指标。参与本研究的参与者分为以下5组：正常人群、高危人群、脑卒中前个体、急性脑卒中患者和脑卒中恢复期患者。分析并比较不同人群中CVHI指标的特征。

结果

先前定义的5组参与者的脑血管V（min）分别为11.39±3.27、9.66±3.18、6.71±3.30、4.13±1.27、6.78±3.09。V（mean）和V（max）与V（min）具有相同的下降趋势。然而，5组参与者的RV分别为62.35±21.11、82.32±31.16、122.72±52.73、137.46±49.56和115.89±55.51。Zcv、WV、DR和CP也与RV具有相同的上升趋势。从正常人群到脑卒中恢复期患者，CVHI评分（<75分）的异常率分别为13.3%、34.7%、74.1%、100%和66.7%。