Indinnimeo M, Cicchini C, Larcinese A, Kanakaki S, Ricci F, Mingazzini P L
Department of Surgery Pietro Valdoni, University of Rome La Sapienza, Rome, Italy.
Eur J Gynaecol Oncol. 2003;24(2):199-201.
Teratomas are neoplasms composed of tissue foreign to the area in which it is found. They are considered to be an acquired neoplastic disease and familial incidence has not been reported. Only one occurrence of teratoma between monozygotic twins has been found in the literature. Here we report the case of two heterozygotic twins with benign cystic teratomas of the ovary as a base for future research for efficacy of an accurate familial follow-up in order to diagnose this neoplasm in early stage and for the molecular understanding of pathogenesis of teratoma.
畸胎瘤是由其所在区域以外的组织构成的肿瘤。它们被认为是一种后天性肿瘤疾病,尚未有家族发病率的报道。文献中仅发现一例单卵双胞胎患畸胎瘤的情况。在此,我们报告一例双卵双胞胎均患有卵巢良性囊性畸胎瘤的病例,以此作为未来研究准确的家族随访疗效的基础,以便早期诊断这种肿瘤,并从分子层面了解畸胎瘤的发病机制。