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成熟性卵巢畸胎瘤的家族性发生。

Familial occurrence of mature ovarian teratomas.

作者信息

Simon A, Ohel G, Neri A, Schenker J G

出版信息

Obstet Gynecol. 1985 Aug;66(2):278-9.

PMID:4022488
Abstract

It has been suggested that genetic predisposing factors play a role in the development of ovarian teratomas. Familial occurrence of these tumors would support this view. Reported herein are identical twins, both of whom had a right ovarian mature teratoma. In both cases the presenting symptoms were acute torsion. The diagnosis was confirmed at laparotomy and subsequent histopathologic examination. The origin of ovarian teratomas seems to be linked to the process of parthenogenesis. This process probably involves a germ cell after its first meiotic division.

摘要

有人提出,遗传易感性因素在卵巢畸胎瘤的发生中起作用。这些肿瘤的家族性发生将支持这一观点。本文报道了一对同卵双胞胎,两人都患有右侧卵巢成熟畸胎瘤。在这两个病例中,主要症状均为急性扭转。诊断通过剖腹手术及随后的组织病理学检查得以证实。卵巢畸胎瘤的起源似乎与孤雌生殖过程有关。这个过程可能涉及一个经过第一次减数分裂后的生殖细胞。

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