文昌鱼和人类中NK同源框基因簇的分散情况。
Dispersal of NK homeobox gene clusters in amphioxus and humans.
作者信息
Luke Graham N, Castro L Filipe C, McLay Kirsten, Bird Christine, Coulson Alan, Holland Peter W H
机构信息
School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, United Kingdom.
出版信息
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5292-5. doi: 10.1073/pnas.0836141100. Epub 2003 Apr 18.
Abstract
The Drosophila melanogaster genome has six physically clustered NK-related homeobox genes in just 180 kb. Here we show that the NK homeobox gene cluster was an ancient feature of bilaterian animal genomes, but has been secondarily split in chordate ancestry. The NK homeobox gene clusters of amphioxus and vertebrates are each split and dispersed at two equivalent intergenic positions. From the ancestral NK gene cluster, only the Tlx-Lbx and NK3-NK4 linkages have been retained in chordates. This evolutionary pattern is in marked contrast to the Hox and ParaHox gene clusters, which are compact in amphioxus and vertebrates, but have been disrupted in Drosophila.
摘要
果蝇的基因组在仅180千碱基对的区域内有6个物理上成簇的与NK相关的同源异型盒基因。我们在此表明，NK同源异型盒基因簇是两侧对称动物基因组的一个古老特征，但在脊索动物的祖先中发生了二次分裂。文昌鱼和脊椎动物的NK同源异型盒基因簇分别在两个等效的基因间位置发生分裂和分散。从祖先的NK基因簇来看，在脊索动物中仅保留了Tlx-Lbx和NK3-NK4的连锁关系。这种进化模式与Hox和ParaHox基因簇形成了显著对比，后者在文昌鱼和脊椎动物中是紧凑的，但在果蝇中已被破坏。
相似文献
1
Dispersal of NK homeobox gene clusters in amphioxus and humans.文昌鱼和人类中NK同源框基因簇的分散情况。
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5292-5. doi: 10.1073/pnas.0836141100. Epub 2003 Apr 18.
2
The amphioxus Hox cluster: deuterostome posterior flexibility and Hox14.文昌鱼的Hox基因簇：后口动物的后部灵活性与Hox14
Evol Dev. 2000 Sep-Oct;2(5):284-93. doi: 10.1046/j.1525-142x.2000.00070.x.
3
The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster.副同源盒基因簇是同源盒基因簇在进化上的姐妹。
Nature. 1998 Apr 30;392(6679):920-2. doi: 10.1038/31933.
4
Evidence for 14 homeobox gene clusters in human genome ancestry.人类基因组祖先中14个同源框基因簇的证据。
Curr Biol. 2000 Sep 7;10(17):1059-62. doi: 10.1016/s0960-9822(00)00676-x.
5
Unexpectedly large number of conserved noncoding regions within the ancestral chordate Hox cluster.出乎意料的是，在原始脊索动物Hox基因簇中存在大量保守的非编码区域。
Dev Genes Evol. 2008 Dec;218(11-12):591-7. doi: 10.1007/s00427-008-0246-8. Epub 2008 Sep 13.
6
Chromosomal mapping of ANTP class homeobox genes in amphioxus: piecing together ancestral genomes.文昌鱼中ANTP类同源框基因的染色体定位：拼凑祖先基因组
Evol Dev. 2003 Sep-Oct;5(5):459-65. doi: 10.1046/j.1525-142x.2003.03052.x.
7
Archetypal organization of the amphioxus Hox gene cluster.文昌鱼Hox基因簇的原型组织。
Nature. 1994 Aug 18;370(6490):563-6. doi: 10.1038/370563a0.
8
No more than 14: the end of the amphioxus Hox cluster.不超过14个：文昌鱼Hox基因簇的末端。
Int J Biol Sci. 2005;1(1):19-23. doi: 10.7150/ijbs.1.19. Epub 2005 Jan 5.
9
Identical genomic organization of two hemichordate hox clusters.两种半索动物 Hox 簇的相同基因组组织。
Curr Biol. 2012 Nov 6;22(21):2053-8. doi: 10.1016/j.cub.2012.08.052. Epub 2012 Oct 11.
10
Colinear and segmental expression of amphioxus Hox genes.文昌鱼Hox基因的共线性和片段性表达。
Dev Biol. 1999 Sep 1;213(1):131-41. doi: 10.1006/dbio.1999.9369.
引用本文的文献
1
Evolution of the Spider Homeobox Gene Repertoire by Tandem and Whole Genome Duplication.基因重复导致蜘蛛同源异型盒基因家族的进化。
Mol Biol Evol. 2023 Dec 1;40(12). doi: 10.1093/molbev/msad239.
2
Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera.鳞翅目同源异型盒基因的多样性、复制和基因组组织。
Genome Res. 2023 Jan;33(1):32-44. doi: 10.1101/gr.277118.122. Epub 2022 Dec 8.
3
Genome of the sea anemone and transcriptome profiles during tentacle regeneration.海葵的基因组及触手再生过程中的转录组图谱。
Front Cell Dev Biol. 2022 Aug 17;10:900321. doi: 10.3389/fcell.2022.900321. eCollection 2022.
4
Wnt antagonist as therapeutic targets in ovarian cancer.Wnt拮抗剂作为卵巢癌的治疗靶点。
Int J Biochem Cell Biol. 2022 Apr;145:106191. doi: 10.1016/j.biocel.2022.106191. Epub 2022 Mar 7.
5
Genes: Roles in Development and Cancer.基因：在发育和癌症中的作用。
Cancers (Basel). 2021 Jun 15;13(12):3005. doi: 10.3390/cancers13123005.
6
Reconstruction of ancient homeobox gene linkages inferred from a new high-quality assembly of the Hong Kong oyster (Magallana hongkongensis) genome.从香港牡蛎（Magallana hongkongensis）基因组的新的高质量组装中推断出古代同源盒基因连接的重建。
BMC Genomics. 2020 Oct 15;21(1):713. doi: 10.1186/s12864-020-07027-6.
7
WNT-β-catenin signalling - a versatile player in kidney injury and repair.WNT-β-catenin 信号通路——肾脏损伤与修复中的多面手。
Nat Rev Nephrol. 2021 Mar;17(3):172-184. doi: 10.1038/s41581-020-00343-w. Epub 2020 Sep 28.
8
The genetic factors of bilaterian evolution.两侧对称动物进化的遗传因素。
Elife. 2020 Jul 16;9:e45530. doi: 10.7554/eLife.45530.
9
Expression of NK cluster genes in the onychophoran : implications for the evolution of NK family genes in nephrozoans.栉蚕中NK簇基因的表达：对肾管动物门NK家族基因进化的启示
Evodevo. 2018 Jul 18;9:17. doi: 10.1186/s13227-018-0105-2. eCollection 2018.
10
A TALE of shrimps: Genome-wide survey of homeobox genes in 120 species from diverse crustacean taxa.虾类的故事：对来自不同甲壳类群的120个物种的同源框基因进行全基因组调查。
F1000Res. 2018 Jan 17;7:71. doi: 10.12688/f1000research.13636.1. eCollection 2018.
本文引用的文献
1
Fluorescent in situ hybridisation to amphioxus chromosomes.文昌鱼染色体的荧光原位杂交
Zoolog Sci. 2002 Dec;19(12):1349-53. doi: 10.2108/zsj.19.1349.
2
The genome sequence of the malaria mosquito Anopheles gambiae.冈比亚按蚊——疟蚊的基因组序列。
Science. 2002 Oct 4;298(5591):129-49. doi: 10.1126/science.1076181.
3
Ciona intestinalis ParaHox genes: evolution of Hox/ParaHox cluster integrity, developmental mode, and temporal colinearity.玻璃海鞘副同源框基因：Hox/副同源框基因簇完整性、发育模式及时间共线性的进化
Mol Phylogenet Evol. 2002 Sep;24(3):412-7. doi: 10.1016/s1055-7903(02)00204-x.
4
Fourfold faster rate of genome rearrangement in nematodes than in Drosophila.线虫基因组重排速率比果蝇快四倍。
Genome Res. 2002 Jun;12(6):857-67. doi: 10.1101/gr.172702.
5
Were vertebrates octoploid?脊椎动物是八倍体吗？
Philos Trans R Soc Lond B Biol Sci. 2002 Apr 29;357(1420):531-44. doi: 10.1098/rstb.2001.1035.
6
Sipunculan ParaHox genes.星虫动物的副同源基因。
Evol Dev. 2001 Jul-Aug;3(4):263-70. doi: 10.1046/j.1525-142x.2001.003004263.x.
7
Characterization of Amphioxus AmphiVent, an evolutionarily conserved marker for chordate ventral mesoderm.文昌鱼AmphiVent的特征分析，一种脊索动物腹侧中胚层的进化保守标记物。
Genesis. 2001 Apr;29(4):172-9. doi: 10.1002/gene.1021.
8
The amphioxus Hox cluster: deuterostome posterior flexibility and Hox14.文昌鱼的Hox基因簇：后口动物的后部灵活性与Hox14
Evol Dev. 2000 Sep-Oct;2(5):284-93. doi: 10.1046/j.1525-142x.2000.00070.x.
9
A primitive sarcopterygian fish with an eyestalk.一种长有眼柄的原始肉鳍鱼类。
Nature. 2001 Mar 1;410(6824):81-4. doi: 10.1038/35065078.
10
Initial sequencing and analysis of the human genome.人类基因组的初步测序与分析。
Nature. 2001 Feb 15;409(6822):860-921. doi: 10.1038/35057062.
Zotero 插件