Köhler J
Klinikum Nürnberg Nord, Prof.-Ernst-Nathan-Strasse 1, 90419 Nürnberg.
Kongressbd Dtsch Ges Chir Kongr. 2002;119:128-32.
From 1986-2001 we treated 31 patients with cystic neoplasms of the pancreas. 13 patients showed a cystadenocarcinoma including one rare case of a serous cystadenocarcinoma. A curative resection (R0) was possible in 10 patients (resection rate: 76.9%). After median 61 months (range 29-144 months) 8 patients are alive without evidence of tumour. 2 patients died 2 months (pneumonia) and 36 months (local recurrence) respectively after operation. The latter case of tumour recurrence showed nodal involvement (pN1) in the Whipple specimen. One patient died 44 months after Whipple procedure with tumour-positive resection margin (R1 Situation) from local recurrence and hepatic spread. Our data reflect the good prognosis of cystic neoplasms of the pancreas reported in literature after curative resection--a result of the different biological behaviour compared with ductal adenocarcinome.
1986年至2001年期间,我们共治疗了31例胰腺囊性肿瘤患者。13例为囊腺癌,其中包括1例罕见的浆液性囊腺癌。10例患者可行根治性切除(R0)(切除率:76.9%)。中位随访61个月(范围29 - 144个月)后,8例患者存活且无肿瘤证据。2例患者分别于术后2个月(肺炎)和36个月(局部复发)死亡。后一例肿瘤复发在Whipple标本中显示有淋巴结转移(pN1)。1例患者在Whipple手术后44个月因局部复发和肝转移,切除边缘肿瘤阳性(R1情况)而死亡。我们的数据反映了文献报道的胰腺囊性肿瘤根治性切除后的良好预后,这是与导管腺癌不同生物学行为的结果。