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食管静脉曲张出血的住院经历及治疗结果

Hospital experience and outcomes for esophageal variceal bleeding.

作者信息

Dy Sydney Morss, Cromwell David M, Thuluvath Paul J, Bass Eric B

机构信息

Division of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

出版信息

Int J Qual Health Care. 2003 Apr;15(2):139-46. doi: 10.1093/intqhc/mzg016.

Abstract

OBJECTIVE

Although higher hospital volume has been associated with better outcomes for many surgical procedures, this relationship does not appear to hold for most common medical diagnoses. We evaluated whether there is a volume-outcome relationship for a rarer and higher-mortality medical diagnosis, esophageal variceal bleeding.

DESIGN

Cross-sectional retrospective study of hospital discharge data.

SETTING

All Maryland hospitals from 1992 through 1996.

STUDY PARTICIPANTS

All patients with diagnosis codes for both esophageal variceal bleeding and cirrhosis in relevant diagnosis-related groups.

MAIN OUTCOME MEASURE

Mortality for esophageal variceal bleeding. We classified hospitals by tertiles of admissions as high (> 17 cases of variceal bleeding per year), medium (12-17 cases per year) or low (< 12 cases per year) volume.

RESULTS

There were seven high-volume, 13 medium-volume, and 29 low-volume hospitals. Overall in-hospital mortality was 15%. After multiple regression was used to adjust for differences in age, sex, ethnicity, emergency room admission, use of procedures, complexity, Medicaid status, transfer status, and clinical variables associated with mortality from variceal bleeding, there were no significant differences between the high-, medium-, and low-volume hospital groups in in-hospital mortality (16%, 15%, and 13%, respectively). There were also no significant differences in hospital charges (dollar 17 000, dollar 15 000, and dollar 14 000, respectively) or length of stay (8.5, 8.7, and 7.8 days, respectively) between hospital volume groups.

CONCLUSIONS

The volume-outcome relationship may not pertain to some medical diseases such as esophageal variceal bleeding. Alternatively, the biases inherent in research using administrative data may make this relationship appear weaker for some medical than for surgical diagnoses in this type of study.

摘要

目的

尽管对于许多外科手术而言,较高的医院手术量与更好的治疗效果相关,但这种关系在大多数常见内科诊断中似乎并不成立。我们评估了对于一种较为罕见且死亡率较高的内科诊断——食管静脉曲张破裂出血,是否存在手术量-治疗效果关系。

设计

对医院出院数据进行横断面回顾性研究。

研究地点

1992年至1996年期间的所有马里兰州医院。

研究参与者

在相关诊断相关组中具有食管静脉曲张破裂出血和肝硬化诊断编码的所有患者。

主要结局指标

食管静脉曲张破裂出血的死亡率。我们将医院按每年入院患者三分位数分为高手术量(每年>17例静脉曲张出血病例)、中手术量(每年12 - 17例病例)或低手术量(每年<12例病例)。

结果

有7家高手术量医院、13家中手术量医院和29家低手术量医院。总体住院死亡率为15%。在使用多元回归对年龄、性别、种族、急诊入院、手术操作使用情况、复杂性、医疗补助状态、转院状态以及与静脉曲张出血死亡率相关的临床变量差异进行调整后,高、中、低手术量医院组的住院死亡率之间无显著差异(分别为16%、15%和13%)。医院费用(分别为17000美元、15000美元和14000美元)或住院时间(分别为8.5天、8.7天和7.8天)在不同手术量医院组之间也无显著差异。

结论

手术量-治疗效果关系可能不适用于某些内科疾病,如食管静脉曲张破裂出血。或者,在这类研究中,使用行政数据进行研究时固有的偏差可能使这种关系在内科诊断中比在外科诊断中显得更弱。

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