Huang Zhi Li, Ong Kee Leong, Goh Sze Yi, Liew Han Lim, Yeoh Kian Hian, Wang De Yun
Department of Otolaryngology, Faculty of Medicine, the National University of Singapore, Singapore.
Otolaryngol Head Neck Surg. 2003 Apr;128(4):510-6. doi: 10.1016/S0194-59980300123-2.
We sought to investigate the pattern, duration, and amplitude of nasal cycle and its response to nasal decongestant.
Ten adult volunteers attended 2 sessions (with and without nasal spray of 0.1% xylometazoline) for consecutive examinations by rhinomanometry and acoustic rhinometry every 10 minutes over 6 hours.
A spontaneous fluctuation in nasal minimum cross-sectional area, volume, and nasal resistances (inspiration and expiration) could be observed in every consecutive measurement. A significant negative correlation (r = -0.33 to -0.70, P < 0.05) between both nasal passages was shown in 5 subjects by rhinomanometry and in 2 subjects by acoustic rhinometry but was not detectable after nasal spray with 0.1% xylometazoline.
A spontaneous fluctuation in nasal patency can be documented every 10 minutes with irregular pattern, frequency, and amplitude. Classic nasal cycle is not a universal phenomenon, which can be abolished by the application of decongestant.
我们试图研究鼻周期的模式、持续时间和幅度及其对鼻减充血剂的反应。
10名成年志愿者参加了2次检查(一次使用0.1%赛洛唑啉鼻喷雾剂,一次不使用),在6小时内每隔10分钟通过鼻阻力计和鼻声反射仪进行连续检查。
在每次连续测量中,均可观察到鼻腔最小横截面积、容积和鼻阻力(吸气和呼气)的自发波动。通过鼻阻力计,5名受试者的双侧鼻腔之间显示出显著的负相关(r = -0.33至-0.70,P < 0.05);通过鼻声反射仪,2名受试者显示出显著负相关,但在使用0.1%赛洛唑啉鼻喷雾剂后未检测到这种相关性。
鼻腔通畅度每10分钟会出现一次自发波动,其模式、频率和幅度不规则。典型的鼻周期并非普遍现象,使用减充血剂可消除该现象。