Lang Amy M
Department of Rehabilitation Medicine, Emory University School of Medicine and Hospitals, Atlanta, GA, USA.
Arch Phys Med Rehabil. 2003 Mar;84(3 Suppl 1):S69-73; quiz S74-5. doi: 10.1053/apmr.2003.50121.
This self-directed learning module highlights that the underlying problem in many types of muscle pain disorders is a distortion of critical structures that causes functional deficits and pain. An objective of treatment is to reverse this distortion, enabling repair of damaged tissues and strengthening of weakened muscles. Administering botulinum toxin type A (BTX-A; Botox) to reduce muscle tone and overactivity warrants consideration as part of an overall treatment approach that includes physical therapy to help restore normal muscle length and biomechanical balance to improve the prospect of ensuring long-term relief from associated pain. This article specifically focuses on pertinent review articles, results of controlled and open-trial data, and case reports to assess the role of BTX-A treatment in chronic pain disorders. OVERALL LEARNING OBJECTIVE: To review the clinical trial data of the safety and efficacy of BTX-A for the treatment of chronic pain syndromes associated with muscle disorders.
这个自主学习模块强调，许多类型的肌肉疼痛障碍的根本问题是关键结构的扭曲，这会导致功能缺陷和疼痛。治疗的目标是扭转这种扭曲，使受损组织得以修复，虚弱的肌肉得以强化。考虑使用A型肉毒毒素（BTX-A；保妥适）来降低肌肉张力和过度活动，这是整体治疗方法的一部分，该方法包括物理治疗，以帮助恢复正常肌肉长度和生物力学平衡，从而提高确保长期缓解相关疼痛的可能性。本文特别关注相关综述文章、对照试验和开放试验数据的结果以及病例报告，以评估BTX-A治疗在慢性疼痛障碍中的作用。总体学习目标：回顾BTX-A治疗与肌肉疾病相关的慢性疼痛综合征的安全性和有效性的临床试验数据。
