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Lamivudine resistance in human T-cell leukemia virus type 1 may be due to a polymorphism at codon 118 (V-->I) of the reverse transcriptase.

作者信息

Toro Carlos, Rodés Berta, Mendoza Carmen de, Soriano Vincent

出版信息

Antimicrob Agents Chemother. 2003 May;47(5):1774;author reply 1774-5. doi: 10.1128/AAC.47.5.1774-1775.2003.

DOI:10.1128/AAC.47.5.1774-1775.2003
PMID:12709359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC153342/
Abstract
摘要

相似文献

1
Lamivudine resistance in human T-cell leukemia virus type 1 may be due to a polymorphism at codon 118 (V-->I) of the reverse transcriptase.1型人类T细胞白血病病毒对拉米夫定耐药可能是由于逆转录酶第118位密码子（缬氨酸→异亮氨酸）的多态性所致。
Antimicrob Agents Chemother. 2003 May;47(5):1774;author reply 1774-5. doi: 10.1128/AAC.47.5.1774-1775.2003.
2
Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.人类嗜T淋巴细胞病毒1型对逆转录酶抑制剂的敏感性：对拉米夫定耐药的证据。
J Infect Dis. 2001 Aug 15;184(4):507-10. doi: 10.1086/322785. Epub 2001 Jul 25.
3
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Mutations at codon 184 in simian immunodeficiency virus reverse transcriptase confer resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.猿猴免疫缺陷病毒逆转录酶第184位密码子的突变赋予了对2',3'-二脱氧-3'-硫代胞苷（-）对映体的抗性。
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J Med Virol. 2007 Nov;79(11):1650-4. doi: 10.1002/jmv.20974.
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Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.齐多夫定、司他夫定和拉米夫定三磷酸酯对来自野生型及耐齐多夫定的1型人类免疫缺陷病毒临床分离株的纯化重组逆转录酶的抑制作用。
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[Lamivudine therapy for chronic hepatitis B].[拉米夫定治疗慢性乙型肝炎]
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Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.人类嗜T淋巴细胞病毒I型对核苷类逆转录酶抑制剂的敏感性。
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Front Med (Lausanne). 2022 Apr 29;9:881547. doi: 10.3389/fmed.2022.881547. eCollection 2022.
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Pathogens. 2020 May 1;9(5):342. doi: 10.3390/pathogens9050342.
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Future Perspectives on Drug Targeting in Adult T Cell Leukemia-Lymphoma.成人T细胞白血病-淋巴瘤中药物靶向治疗的未来展望
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Susceptibility of primary HTLV-1 isolates from patients with HTLV-1-associated myelopathy to reverse transcriptase inhibitors.原发性 HTLV-1 分离株对逆转录酶抑制剂的敏感性与 HTLV-1 相关脊髓病患者。
Viruses. 2011 May;3(5):469-83. doi: 10.3390/v3050469. Epub 2011 May 5.
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Effect of phosphonated carbocyclic 2'-oxa-3'-aza-nucleoside on human T-cell leukemia virus type 1 infection in vitro.膦酸化碳环2'-氧杂-3'-氮杂核苷对人1型T细胞白血病病毒体外感染的影响。
Antimicrob Agents Chemother. 2008 Jan;52(1):54-64. doi: 10.1128/AAC.00470-07. Epub 2007 Oct 29.
6
Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial.齐多夫定联合拉米夫定治疗I型人嗜T淋巴细胞病毒相关脊髓病：一项随机试验。
Retrovirology. 2006 Sep 19;3:63. doi: 10.1186/1742-4690-3-63.
7
Adult T cell leukemia lymphoma.成人T细胞白血病淋巴瘤
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本文引用的文献

1
Effect of lamivudine on transmission of human T-cell lymphotropic virus type 1 to adult peripheral blood mononuclear cells in vitro.拉米夫定对人嗜T细胞病毒1型体外感染成人外周血单个核细胞的影响。
Antimicrob Agents Chemother. 2002 Sep;46(9):3080-3. doi: 10.1128/AAC.46.9.3080-3083.2002.
2
Mechanisms of resistance to antiretroviral drugs--clinical implications.抗逆转录病毒药物耐药机制——临床意义
AIDS Rev. 2002 Apr-Jun;4(2):64-82.
3
The effect of antiretroviral therapy on HTLV infection.抗逆转录病毒疗法对人类嗜T淋巴细胞病毒感染的影响。
Virus Res. 2001 Oct 30;78(1-2):93-100. doi: 10.1016/s0168-1702(01)00287-8.
4
Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.人类嗜T淋巴细胞病毒1型对逆转录酶抑制剂的敏感性：对拉米夫定耐药的证据。
J Infect Dis. 2001 Aug 15;184(4):507-10. doi: 10.1086/322785. Epub 2001 Jul 25.
5
Susceptibility of the porcine endogenous retrovirus to reverse transcriptase and protease inhibitors.猪内源性逆转录病毒对逆转录酶和蛋白酶抑制剂的敏感性。
J Virol. 2001 Jan;75(2):1048-53. doi: 10.1128/JVI.75.2.1048-1053.2001.
6
In vivo fluctuation of HTLV-I and HTLV-II proviral load in patients receiving antiretroviral drugs.接受抗逆转录病毒药物治疗的患者体内人嗜T淋巴细胞病毒I型和II型前病毒载量的波动情况。
J Acquir Immune Defic Syndr. 2000 Jun 1;24(2):189-93. doi: 10.1097/00126334-200006010-00017.
7
Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine.野生型和YMDD突变型鼠白血病病毒逆转录酶对2'，3'-二脱氧-3'-硫代胞苷具有抗性。
J Virol. 2000 Jul;74(14):6669-74. doi: 10.1128/jvi.74.14.6669-6674.2000.
8
A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V.一种新型的人类免疫缺陷病毒1型逆转录酶突变模式在不存在184V突变的情况下赋予了对拉米夫定的表型耐药性。
Antimicrob Agents Chemother. 2000 Mar;44(3):568-73. doi: 10.1128/AAC.44.3.568-573.2000.
9
Effect of lamivudine on human T-cell leukemia virus type 1 (HTLV-1) DNA copy number, T-cell phenotype, and anti-tax cytotoxic T-cell frequency in patients with HTLV-1-associated myelopathy.拉米夫定对成人T细胞白血病病毒1型（HTLV-1）相关脊髓病患者HTLV-1 DNA拷贝数、T细胞表型及抗Tax细胞毒性T细胞频率的影响
J Virol. 1999 Dec;73(12):10289-95. doi: 10.1128/JVI.73.12.10289-10295.1999.