Held P, Dorenbeck U, Seitz J, Fründ R, Albrich H
Department of Diagnostic Radiology, University of Regensburg, 93042 Regensburg, Germany.
J Neuroradiol. 2003 Mar;30(2):83-90.
The aim of this study was to assess the potential of heavily T2* weighted 2D spoiled gradient echo multiecho sequence MEDIC (multi echo data image combination) with magnetization transfer saturation pulse (MTS) for detecting abnormality of the cervical spinal cord.
11 patients, 5 women and 6 men aged from 14 to 79 years (mean age 51.18 years), with traumatic, hemolytic-hemorrhagic or neoplastic diseases of the cervical spinal cord were examined with MRI. In cases with suspected myelopathy, the feasibility of the 2D spoiled gradient echo multiecho sequence MEDIC with MTS was evaluated in comparison with the results of spin echo T1W, spin echo T2W, multi echo (TSE in our case) and spin-echo multi-echo technique with magnetization preparation (turbo inversion recovery--TIR--in our case) sequences.
Distortion of the "H" sign was found in all but one case. Hemorrhage was best shown by MEDIC, massive edema was very well visible using MEDIC, TIR and TSE T2W, whereas mild edema was visible with MEDIC only.
Our preliminary experience in 11 patients shows that MEDIC can be used for the diagnosis of cervical spinal cord pathology.
本研究旨在评估采用带有磁化传递饱和脉冲(MTS)的重T2*加权二维扰相梯度回波多回波序列MEDIC(多回波数据图像合成)检测颈髓异常的潜力。
对11例年龄在14至79岁(平均年龄51.18岁)、患有颈髓创伤性、溶血性出血性或肿瘤性疾病的患者进行了MRI检查。对于疑似脊髓病的病例,将带有MTS的二维扰相梯度回波多回波序列MEDIC的可行性与自旋回波T1加权、自旋回波T2加权、多回波(我们病例中的快速自旋回波)以及带有磁化准备的自旋回波多回波技术(我们病例中的快速反转恢复——TIR)序列的结果进行了比较评估。
除1例病例外,其余所有病例均发现“H”征变形。MEDIC对出血显示最佳,MEDIC、TIR和快速自旋回波T2加权对大量水肿显示得非常清晰,而轻度水肿仅在MEDIC上可见。
我们对11例患者的初步经验表明,MEDIC可用于颈髓病变的诊断。