Cliff Julie, Simango Alexandra, Augusto Orvalho, Van Der Paal Lieve, Biellik Robin
Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
J Infect Dis. 2003 May 15;187 Suppl 1:S51-7. doi: 10.1086/368058.
This study assessed the effect of urban supplemental measles vaccination campaigns (1997-1999) in Mozambique that targeted children aged 9-59 months. Reported measles cases were analyzed to the end of 2001 to determine campaign impact. Hospital inpatient data were collected in the national capital and in three provincial capitals where epidemics occurred the year after the campaigns. Measles epidemics followed campaigns in the capital city, in 4 of 9 provincial capitals, and in 39 of 126 districts. Reasons for limited campaign impact included a low proportion of urban dwellers, the geographic location of some provincial capitals, the limited target age group, and low routine and campaign coverage. Routine immunization and disease surveillance should be strengthened and campaigns must achieve >90% coverage and target wider age groups and geographic areas in order to reach a high proportion of persons susceptible to measles.
本研究评估了莫桑比克1997 - 1999年针对9至59个月儿童开展的城市补充麻疹疫苗接种活动的效果。对报告的麻疹病例进行分析，直至2001年底，以确定活动的影响。在国家首都以及活动开展后次年发生疫情的三个省会城市收集了医院住院数据。在首都、9个省会中的4个以及126个地区中的39个地区，活动之后出现了麻疹疫情。活动影响有限的原因包括城市居民比例低、一些省会城市的地理位置、目标年龄组有限以及常规免疫和活动覆盖率低。应加强常规免疫和疾病监测，活动必须实现>90%的覆盖率，并针对更广泛的年龄组和地理区域，以便让高比例的麻疹易感人群得到接种。
