Luo Q, Yan J, Zhang S
Department of Hygiene, Hubei Medical University, Wuhan 430071, China.
Wei Sheng Yan Jiu. 2000 Mar 30;29(2):115-7.
A purified component of lycium barbarum polysaccharide (LBP-X) was isolated from lycium barbarum L. by DEAE ion-exchange cellulose and sephacryl gel chromatography. LBP-X was tested on five different doses (5, 10, 20, 50 and 100 mg.kg-1.d-1) in mice. The results showed that LBP-X induced a remarkable adaptability to exercise load, enhanced resistance and accelerated elimination of fatigue. LBP-X could enhance the storage of muscle and liver glycogen, increase the activity of LDH before and after swimming, decrease the increase of blood urea nitrogen (BUN) after strenuous exercise, and accelerate the clearance of BUN after exercise. The dosage of LBP-X 10 mg.kg-1.d-1 was the best amount among the five tested doses.
采用DEAE离子交换纤维素和葡聚糖凝胶柱色谱法从宁夏枸杞中分离出一种纯化的枸杞多糖组分（LBP-X）。对小鼠进行了5种不同剂量（5、10、20、50和100mg·kg-1·d-1）的LBP-X测试。结果表明，LBP-X能显著提高对运动负荷的适应性，增强抵抗力并加速疲劳消除。LBP-X可增加肌肉和肝糖原储备，提高游泳前后乳酸脱氢酶（LDH）活性，减少剧烈运动后血尿素氮（BUN）的升高，并加速运动后BUN的清除。在5种测试剂量中，LBP-X 10mg·kg-1·d-1的剂量效果最佳。
