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多糖的提取、结构特征及生物学功能:综述。

Extraction, Structural Characterization, and Biological Functions of Polysaccharides: A Review.

机构信息

China-Malaysia National Joint Laboratory, Biomedical Research Center, Northwest Minzu University, Lanzhou 730124, China.

College of Life Science and Engineering, Northwest Minzu University, Lanzhou 730124, China.

出版信息

Biomolecules. 2019 Aug 21;9(9):389. doi: 10.3390/biom9090389.

DOI:10.3390/biom9090389
PMID:31438522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6770593/
Abstract

polysaccharides (LBPs), as bioactive compounds extracted from L. fruit, have been widely explored for their potential health properties. The extraction and structural characterization methods of LBPs were reviewed to accurately understand the extraction method and structural and biological functions of LBPs. An overview of the biological functions of LBPs, such as antioxidant function, antitumor activity, neuroprotective effects, immune regulating function, and other functions, were summarized. This review provides an overview of LBPs and a theoretical basis for further studying and extending the applications of LBPs in the fields of medicine and food.

摘要

多糖(LBPs)是从灵芝中提取的生物活性化合物,其潜在的健康特性已被广泛研究。本文综述了 LBPs 的提取和结构特征方法,以准确了解 LBPs 的提取方法、结构和生物学功能。总结了 LBPs 的生物学功能,如抗氧化功能、抗肿瘤活性、神经保护作用、免疫调节功能等。本文综述了 LBPs,为进一步研究和拓展 LBPs 在医药和食品领域的应用提供了理论基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/6770593/d8e9d6f20ca8/biomolecules-09-00389-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/6770593/ea56d46a1fc8/biomolecules-09-00389-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/6770593/d8e9d6f20ca8/biomolecules-09-00389-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/6770593/ea56d46a1fc8/biomolecules-09-00389-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e306/6770593/d8e9d6f20ca8/biomolecules-09-00389-g002.jpg

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Carbohydr Polym. 2019 Apr 15;210:412-428. doi: 10.1016/j.carbpol.2019.01.064. Epub 2019 Jan 29.
3
The estrogen‑like protective effect of Lycium barbarum polysaccharides in reducing oxidative stress on myocardial cells from ovariectomized rats.
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Int J Mol Sci. 2025 Jul 23;26(15):7091. doi: 10.3390/ijms26157091.
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Lycium barbarum glycopeptide mitigates retinal ischemia-reperfusion injury through its anti-inflammatory, anti- senescence, and anti-apoptosis properties.枸杞糖肽通过其抗炎、抗衰老和抗凋亡特性减轻视网膜缺血再灌注损伤。
Sci Rep. 2025 Jul 30;15(1):27806. doi: 10.1038/s41598-025-10763-y.
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Identification of antagonistic activity against , and liquid fermentation of biocontrol isolated from wolfberry () rhizosphere soil.枸杞(Lycium barbarum)根际土壤中分离出的生防菌对[具体对象]拮抗活性的鉴定及液体发酵
Front Microbiol. 2025 Jul 15;16:1601945. doi: 10.3389/fmicb.2025.1601945. eCollection 2025.
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Diversity and Correlation Analysis of Differential Amino Acid Metabolites and Dominant Endophytic Bacteria in Fruits at Different Stages.不同发育阶段果实中差异氨基酸代谢产物与优势内生细菌的多样性及相关性分析
Genes (Basel). 2025 Jul 18;16(7):836. doi: 10.3390/genes16070836.
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Biomed Pharmacother. 2019 Feb;110:20-28. doi: 10.1016/j.biopha.2018.11.012. Epub 2018 Nov 17.
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Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice.枸杞多糖通过抑制 PI3K/Akt 通路介导的雄性小鼠异常自噬来减轻糖尿病睾丸功能障碍。
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