枯草芽孢杆菌酰基脂质去饱和酶是一种Δ5去饱和酶。
The Bacillus subtilis acyl lipid desaturase is a delta5 desaturase.
作者信息
Altabe Silvia G, Aguilar Pablo, Caballero Gerardo M, de Mendoza Diego
机构信息
Instituto de Biología Molecular y Celular de Rosario, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, S2002LRK-Rosario, Argentina.
出版信息
J Bacteriol. 2003 May;185(10):3228-31. doi: 10.1128/JB.185.10.3228-3231.2003.
Abstract
Bacillus subtilis was recently reported to synthesize unsaturated fatty acids (UFAs) with a double bond at positions delta5, delta7, and delta9 (M. H. Weber, W. Klein, L. Muller, U. M. Niess, and M. A. Marahiel, Mol. Microbiol. 39:1321-1329, 2001). Since this finding would have considerable importance in the double-bond positional specificity displayed by the B. subtilis acyl lipid desaturase, we have attempted to confirm this observation. We report that the double bond of UFAs synthesized by B. subtilis is located exclusively at the delta5 position, regardless of the growth temperature and the length chain of the fatty acids.
摘要
最近有报道称，枯草芽孢杆菌能够合成在δ5、δ7和δ9位带有双键的不饱和脂肪酸（UFAs）（M. H. 韦伯、W. 克莱因、L. 米勒、U. M. 尼斯和M. A. 马拉希尔，《分子微生物学》39:1321 - 1329，2001年）。鉴于这一发现对于枯草芽孢杆菌酰基脂质去饱和酶所显示的双键位置特异性具有相当重要的意义，我们试图证实这一观察结果。我们报告称，无论生长温度和脂肪酸链的长度如何，枯草芽孢杆菌合成的不饱和脂肪酸的双键仅位于δ5位。
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