Wojas-Pelc Anna, Stepień Artur, Lipko-Godlewska Sylwia, Wielowieyska-Szybińska Dorota, Zabińska-Płazak Ewa, Kiełtyka Agnieszka
Katedra i Klinika Dermatologii Collegium Medicum Uniwersytetu Jagiellońskiego, 31-501 Kraków, ul. Kopernika 19.
Przegl Lek. 2002;59(12):973-6.
Systemic sclerosis (SSc) is a multisystem connective tissue disorder characterized by excessive accumulation of the extracellular matrix. About 90% of the patients with SSc have detectable gastrointestinal tract involvement, 50% of these patients have clinically important manifestations. The aim of the study was estimation of the connection between subjective symptoms from the esophagus and results of the esophageal scintigraphy. 30 patients with systemic sclerosis were comprised to the study. Esophageal scintigraphy was performed in each patients, as well as questionnaire about type, intensity and frequency of esophageal dysmotility. Also it estimated was stiffness of the skin according to modified Rodnan score. Independent of esophageal dysmotility symptoms which were noted by patients, esophageal scintigraphy registered changes in 97% of the patients. The most often esophageal dysmotility was observed in lower part of the esophagus. Statistically Dysmolity of the central portion of the esophagus was observed more often in patients with diagnosed ISSc.
系统性硬化症（SSc）是一种多系统结缔组织疾病，其特征是细胞外基质过度积累。约90%的SSc患者存在可检测到的胃肠道受累，其中50%的患者有具有临床意义的表现。本研究的目的是评估食管主观症状与食管闪烁扫描结果之间的关联。30例系统性硬化症患者纳入本研究。对每位患者进行了食管闪烁扫描，并就食管运动障碍的类型、强度和频率进行了问卷调查。同时根据改良的罗德南评分评估皮肤硬度。无论患者所记录的食管运动障碍症状如何，食管闪烁扫描在97%的患者中发现了变化。最常观察到食管运动障碍的部位是食管下段。经统计学分析，确诊为弥漫性皮肤型系统性硬化症（ISSc）的患者食管中部运动障碍更为常见。
