Mayes Jane, Bliss Julie, Griffiths Peter
Kensington and Chelsea Primary Care Trust, London.
Br J Community Nurs. 2003 Apr;8(4):172-5. doi: 10.12968/bjcn.2003.8.4.11193.
Community health practitioners are frequently faced with the problem of indwelling catheters failing to drain. This mini-review examines the evidence regarding the effectiveness of citric acid-based bladder washout solutions (solution G, solution R), compared with saline for preventing blockage of long-term catheters in older adults. Although there is some evidence on the effect of citric acid solutions in laboratory conditions, the search yielded no evidence measuring catheter patency in humans. Only one randomized controlled trial addressing the use of citric acid solutions with human subjects was found. This provided some confirmation that solution G had immediate effect but gave no evidence of long-term benefit. No difference was apparent on examination of catheter tips. As the evidence is weak, practitioners should consider the use of citric acid maintenance solution as non-routine and only following formal evaluation in a one-off trial on appropriate patients.
社区卫生从业者经常面临留置导管引流不畅的问题。本综述探讨了与生理盐水相比,基于柠檬酸的膀胱冲洗液(溶液G、溶液R)在预防老年人长期导管堵塞方面有效性的证据。尽管在实验室条件下有一些关于柠檬酸溶液效果的证据,但检索未找到衡量人体导管通畅性的证据。仅发现一项针对人体使用柠檬酸溶液的随机对照试验。这提供了一些证据证实溶液G有即刻效果,但未证明有长期益处。检查导管尖端时未发现明显差异。由于证据不足,从业者应将柠檬酸维持溶液的使用视为非常规方法,仅在对合适患者进行一次性试验的正式评估后使用。