Aibinu I E, Ohaegbulam V C, Adenipekun E A, Ogunsola F T, Odugbemi T O, Mee B J
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria.
J Clin Microbiol. 2003 May;41(5):2197-200. doi: 10.1128/JCM.41.5.2197-2200.2003.
Over a 9-month period, 8 of 40 nonduplicate isolates of Enterobacter spp. producing extended-spectrum beta-lactamase (ESBL) were detected for the first time from two hospitals in Lagos, Nigeria. Microbiologic and molecular analysis confirmed the presence of ESBL. Only four isolates transferred ESBL resistance as determined by the conjugation test, and pulsed-field gel electrophoresis showed genetically unrelated isolates.
在9个月的时间里,从尼日利亚拉各斯的两家医院首次检测到40株非重复分离的产超广谱β-内酰胺酶(ESBL)肠杆菌属菌株中的8株。微生物学和分子分析证实了ESBL的存在。通过接合试验确定,只有4株分离株传递了ESBL耐药性,脉冲场凝胶电泳显示分离株在基因上不相关。