1998年法国大肠埃希菌中超广谱β-内酰胺酶的调查。法国研究小组。
A 1998 survey of extended-spectrum beta-lactamases in Enterobacteriaceae in France. The French Study Group.
作者信息
De Champs C, Sirot D, Chanal C, Bonnet R, Sirot J
机构信息
Laboratoire de Bactériologie, Faculté de Médecine, Université d'Auvergne, 63001 Clermont-Ferrand Cedex, France.
出版信息
Antimicrob Agents Chemother. 2000 Nov;44(11):3177-9. doi: 10.1128/AAC.44.11.3177-3179.2000.
Abstract
In a 3-month period in 1998, 79 consecutive isolates of Enterobacteriaceae producing an extended-spectrum beta-lactamase (ESBL) were collected. ESBLs were predominantly TEM derivatives (74 of 79): TEM-24-like (40 isolates), TEM-3-like (29 isolates), TEM-21 (3 isolates), and TEM-4 and TEM-52 (1 isolate each). Four isolates produced SHV derivatives SHV-4 (three isolates) and SHV-5 (one isolate), and one strain produced a CTX-M-3 enzyme. The high proportion of TEM-24-like-producing Enterobacter aerogenes isolates (36 of 79) suggests the occurrence of an epidemic strain in France.
摘要
1998年的3个月期间，收集了79株连续分离的产超广谱β-内酰胺酶（ESBL）的肠杆菌科细菌。ESBL主要是TEM衍生型（79株中的74株）：TEM-24样型（40株）、TEM-3样型（29株）、TEM-21（3株）以及TEM-4和TEM-52（各1株）。4株产生SHV衍生型SHV-4（3株）和SHV-5（1株），1株产生CTX-M-3酶。产TEM-24样型的产气肠杆菌分离株比例很高（79株中的36株），提示法国出现了一种流行菌株。
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