Baehrecke Eric H
Center for Biosystems Research, University of Maryland Biotechnology Institute, College Park, MD 20742, USA.
Dev Cell. 2003 May;4(5):608-9. doi: 10.1016/s1534-5807(03)00134-5.
Cytochrome c is a critical regulator of apoptosome assembly, caspase activation, and programmed cell death. Recent work demonstrates that cytochrome c and caspases function in Drosophila sperm cell differentiation and indicates that caspase activity can be regulated in a subcellular manner in cells that live.
细胞色素c是凋亡小体组装、半胱天冬酶激活和程序性细胞死亡的关键调节因子。最近的研究表明,细胞色素c和半胱天冬酶在果蝇精子细胞分化中发挥作用,并表明半胱天冬酶活性可以在存活细胞中以亚细胞方式受到调节。