• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内因性肾病所致急性肾衰竭:1122例病例回顾

Acute renal failure due to intrinsic renal diseases: review of 1122 cases.

作者信息

Prakash Jai, Sen D, Kumar N Sarat, Kumar H, Tripathi L K, Saxena R K

机构信息

Department of Nephrology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

Ren Fail. 2003 Mar;25(2):225-33. doi: 10.1081/jdi-120018723.

DOI:10.1081/jdi-120018723
PMID:12739829
Abstract

In this study we have analyzed incidence, causes and clinical course of ARF due to primary intrarenal disease other than acute tubular necrosis. Thousand hundred and twenty two cases of ARF of diverse etiology were studied over a period of 16 years; July 1984 to Dec, 1999. Surgical ARF 231 (20.6%) were not included in the present study. Intrinsic renal diseases were responsible for ARF in 891 (79.4%) of cases. The most common intrinsic renal diseases 705 (79.4%) causing ARF were ischemic/toxic acute tubular necrosis, but not included in this study. Acute renal failure was related to acute glomerulonephritis (9.3%), acute interstitial nephritis (7%), and renal cortical necrosis in (4.6%) of cases. Therefore intrinsic renal diseases other than ATN were the causative factor for acute renal failure in 186 (20.8%) patients in our study. Crescentic (51.8%) and endocapillary proliferative glomerulonephritis (34.9%), were the main glomerular diseases responsible for ARF and 75.9% of GN was related to infectious etiology. Fifty three percent of acute interstitial nephritis was drug induced and in 25 (40%) patients it was related to an infectious etiology. Renal cortical necrosis due to HUS was observed in 16 (39%) children and majority (76.47%) of the cases had a diarrhoeal prodrome. Obstetrical complications were the main causes (61%) of cortical necrosis in adults with acute renal failure. Thus, intrinsic renal diseases other than ATN were responsible for ARF in 186 (20.8%) cases. Post-infectious glomerulonephritis, acute interstitial nephritis and renal cortical necrosis (complicating HUS in children and obstetrical complications in adult) are the main causes of acute renal failure in our study. Both acute GN and interstitial nephritis had excellent prognosis, however renal cortical necrosis was associated with a very high mortality.

摘要

在本研究中,我们分析了除急性肾小管坏死外,原发性肾内疾病所致急性肾衰竭(ARF)的发病率、病因及临床病程。在1984年7月至1999年12月的16年间,我们研究了1222例病因各异的ARF病例。本研究未纳入231例(20.6%)外科性ARF。891例(79.4%)病例的ARF由肾内疾病引起。导致ARF的最常见肾内疾病为缺血性/中毒性急性肾小管坏死,共705例(79.4%),但本研究未纳入。急性肾衰竭与急性肾小球肾炎(9.3%)、急性间质性肾炎(7%)及肾皮质坏死(4.6%)相关。因此,在我们的研究中,186例(20.8%)患者的急性肾衰竭病因是除急性肾小管坏死外的其他肾内疾病。新月体性(51.8%)和毛细血管内增生性肾小球肾炎(34.9%)是导致ARF的主要肾小球疾病,75.9%的肾小球肾炎与感染性病因相关。53%的急性间质性肾炎由药物引起,25例(40%)患者与感染性病因有关。16例(39%)儿童因溶血尿毒综合征(HUS)出现肾皮质坏死,大多数病例(76.47%)有腹泻前驱症状。产科并发症是急性肾衰竭成人患者肾皮质坏死的主要原因(61%)。因此,186例(20.8%)病例的ARF由除急性肾小管坏死外的其他肾内疾病引起。感染后肾小球肾炎、急性间质性肾炎和肾皮质坏死(儿童并发HUS,成人并发产科并发症)是我们研究中急性肾衰竭的主要原因。急性肾小球肾炎和急性间质性肾炎预后均良好,然而肾皮质坏死的死亡率极高。

相似文献

1
Acute renal failure due to intrinsic renal diseases: review of 1122 cases.内因性肾病所致急性肾衰竭:1122例病例回顾
Ren Fail. 2003 Mar;25(2):225-33. doi: 10.1081/jdi-120018723.
2
Decreasing incidence of renal cortical necrosis in patients with acute renal failure in developing countries: a single-centre experience of 22 years from Eastern India.发展中国家急性肾衰竭患者肾皮质坏死发病率降低:来自印度东部的一项22年单中心经验
Nephrol Dial Transplant. 2007 Apr;22(4):1213-7. doi: 10.1093/ndt/gfl761. Epub 2007 Jan 31.
3
Etiologies and outcome of acute renal insufficiency in older adults: a renal biopsy study of 259 cases.老年人急性肾功能不全的病因及预后:259例肾活检研究
Am J Kidney Dis. 2000 Mar;35(3):433-47. doi: 10.1016/s0272-6386(00)70196-x.
4
Acute renal failure amongst children in a tropical environment.
Int J Artif Organs. 1987 Mar;10(2):97-101.
5
Acute renal failure complicating rifampicin therapy.利福平治疗引发的急性肾衰竭
J Assoc Physicians India. 2001 Sep;49:877-80.
6
Renal biopsy findings in acute renal failure in the cohort of patients in the Spanish Registry of Glomerulonephritis.西班牙肾小球肾炎登记处患者队列中急性肾衰竭的肾活检结果。
Clin J Am Soc Nephrol. 2008 May;3(3):674-81. doi: 10.2215/CJN.04441007. Epub 2008 Mar 19.
7
[Acute renal insufficiency].[急性肾功能不全]
Rev Med Liege. 1995 Apr;50(4):153-62.
8
[Acute renal failure: pathophysiology and clinical management].[急性肾衰竭:病理生理学与临床管理]
Dtsch Med Wochenschr. 2007 Nov;132(48):2569-78. doi: 10.1055/s-2007-993100.
9
Acute renal failure in north Indian children.印度北部儿童的急性肾衰竭
Indian J Med Res. 1990 Dec;92:404-8.
10
Spectrum of acute kidney injury in a tertiary care hospital in Cairo.开罗一家三级护理医院急性肾损伤的谱分析
Arab J Nephrol Transplant. 2011 May;4(2):83-6.

引用本文的文献

1
Complement-mediated hemolytic uremic syndrome associated with postpartum hemorrhage: case series and systematic review of individual participant data.与产后出血相关的补体介导的溶血性尿毒症综合征:病例系列及个体参与者数据的系统评价
Res Pract Thromb Haemost. 2024 Oct 3;8(8):102579. doi: 10.1016/j.rpth.2024.102579. eCollection 2024 Nov.
2
Phytochemical, acute toxicity and renal protective appraisal of Ajuga parviflora hydromethanolic leaf extract against CCl induced renal injury in rats.浅析琉璃苣叶水醇提物的化学成分、急性毒性及其对 CCl4 诱导的大鼠肾损伤的保护作用。
BMC Complement Med Ther. 2021 Jul 12;21(1):198. doi: 10.1186/s12906-021-03360-9.
3
Acute kidney injury in hospitalized patients who underwent percutaneous kidney biopsy for histological diagnosis of their renal disease.
因肾脏疾病行经皮肾活检术住院患者的急性肾损伤。
BMC Nephrol. 2019 Aug 13;20(1):315. doi: 10.1186/s12882-019-1514-8.
4
The role of medications and their management in acute kidney injury.药物及其管理在急性肾损伤中的作用。
Integr Pharm Res Pract. 2015 May 18;4:21-29. doi: 10.2147/IPRP.S52930. eCollection 2015.
5
Biopsy series of acute kidney injury from a tertiary care referral center in south India.来自印度南部一家三级医疗转诊中心的急性肾损伤活检系列。
J Nephropharmacol. 2015 Jan 1;4(1):43-45. eCollection 2015.
6
Changing picture of renal cortical necrosis in acute kidney injury in developing country.发展中国家急性肾损伤中肾皮质坏死情况的变化
World J Nephrol. 2015 Nov 6;4(5):480-6. doi: 10.5527/wjn.v4.i5.480.
7
Changing epidemiology of community-acquired acute kidney injury in developing countries: analysis of 2405 cases in 26 years from eastern India.发展中国家社区获得性急性肾损伤流行病学的变化:对印度东部26年里2405例病例的分析
Clin Kidney J. 2013 Apr;6(2):150-5. doi: 10.1093/ckj/sfs178. Epub 2013 Feb 6.
8
Toxic renal injury at a glance.急性中毒性肾损伤概述。
J Renal Inj Prev. 2012 Jan 1;1(1):15-6. doi: 10.12861/jrip.2012.07. eCollection 2012.
9
Acute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging population.抗结核药物导致的急性肾损伤:老龄化人群中的五年经验。
BMC Infect Dis. 2014 Jan 13;14:23. doi: 10.1186/1471-2334-14-23.
10
Community-acquired acute kidney injury in tropical countries.热带国家获得性急性肾损伤。
Nat Rev Nephrol. 2013 May;9(5):278-90. doi: 10.1038/nrneph.2013.36. Epub 2013 Mar 5.