Wu Xiaoming, Dong Xiuzhen, Qin Mingxin, Fu Feng, Wang Yuemin, You Fusheng, Xiang Haiyan, Liu Ruigang, Shi Xuetao
Department of Medical Electronic Engineering, Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an 710032.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2003 Mar;20(1):49-51.
The in vivo measurements of rabbit brain tissue impedance were taken under both normal and ischemic conditions by using two-electrode measurement method in the frequency range from 0.1 Hz to 1 MHz. The dynamic images about the resistivity of cerebral ischemia were reconstructed based on a 16-electrode system. The results of in vivo measurement showed that the ratio of impedance increased can be as high as 75% at frequencies lower than 10 Hz. In the range from 1 KHz to 1 MHz, the ratio showed a constant value of 15%. The electrical impedance tomography (EIT) images obtained suggested that the regions of impedance changes highly correspond to the position of ischemia. It is confirmed that the brain function changes caused by local deficiency of blood can be detected and imaged by EIT method.
采用两电极测量方法，在0.1 Hz至1 MHz的频率范围内，对正常和缺血条件下的兔脑组织阻抗进行了体内测量。基于16电极系统重建了脑缺血电阻率的动态图像。体内测量结果表明，在低于10 Hz的频率下，阻抗增加率可高达75%。在1 kHz至1 MHz范围内，该比率显示为15%的恒定值。获得的电阻抗断层成像（EIT）图像表明，阻抗变化区域与缺血位置高度对应。证实了通过EIT方法可以检测和成像局部血液缺乏引起的脑功能变化。
