Sipe J C
Acta Neuropathol. 1976 May 18;35(1):69-76. doi: 10.1007/BF00688944.
Intercellular junctions were commonly observed in a human syncitial meningioma maintained in organ culture for up to 44 days in vitro (DIV) using gelatin sponge foam matrices. The junctions were identified as one of three types: desmosomes; tight junctions; or gap junctions. Of the three types, gap junctions were frequently encountered and showed preservation of their characteristic ladder-like substructure. The results suggest that organ culture provides an environment that may facilitate correlation of the structure and function of gap junctions between coupled human meningioma cells.
使用明胶海绵泡沫基质在体外培养长达44天（体外培养天数）的人合胞体脑膜瘤中通常可观察到细胞间连接。这些连接被鉴定为三种类型之一：桥粒；紧密连接；或缝隙连接。在这三种类型中，缝隙连接经常出现，并显示出其特征性梯状亚结构的保留。结果表明，器官培养提供了一个环境，可能有助于关联耦合的人脑膜瘤细胞之间缝隙连接的结构和功能。
