Taira Y, Ogata H, Tsuchiyama H
Acta Pathol Jpn. 1976 Mar;26(2):223-8. doi: 10.1111/j.1440-1827.1976.tb00875.x.
The incidence of primary adenoacanthoma of the stomach is extremely low. In the Sasebo City Hospital, there were only two autopsy cases of adenoacanthoma among 46 cases of gastric cancer during the past four years. The first case was a 45-year-old female with metachronous triple cancers; adenoacanthoma of the stomach, squamous cell carcinoma of the uterus and squamous cell carcinoma of the tongue. Histological examination showed muconodular adenoacarcinoma of the stomach at the time of first operation and adenocanthoma at the time of autopsy. These two cases suggest that adenoacanthomas of the stomach may originate from squamous metaplasia or squamous differentiation of a preexisting glandular carcinoma.
胃原发性腺棘皮瘤的发病率极低。在佐世保市立医院，过去四年间46例胃癌病例中仅有两例腺棘皮瘤尸检病例。第一例是一名45岁女性，患有异时性三重癌；胃腺棘皮瘤、子宫鳞状细胞癌和舌鳞状细胞癌。组织学检查显示首次手术时为胃黏液结节性腺癌，尸检时为腺棘皮瘤。这两例病例提示胃腺棘皮瘤可能起源于先前存在的腺癌的鳞状化生或鳞状分化。
