Kaimori M, Takaya H, Suga M, Tanno H, Nakamura K, Kurotaki H
Department of Pathology, Aomori Prefectural Central Hospital, Japan.
No To Shinkei. 1992 Jan;44(1):71-6.
The authors describe an autopsy case of a 68-year-old man with four primary cancers diagnosed at autopsy including malignant meningioma, early esophageal cancer, early gastric cancer and lung cancer. Recently, the number of patients with four and five primary cancers has been increasing. According to the Annual of the Pathological Autopsy Cases in Japan, 156 cases were reported during 16 years from 1974 to 1989. In this series, cancers were detected most frequently in stomach, colon, lung, prostate, liver and esophagus. However, only two cases with four and five primary cancers including malignant meningioma were reported. Because occult cancers like prostatic cancers are unexpectedly diagnosed at autopsy, the incidence of four and five primary cancers including malignant meningioma seems to be higher when the central nervous system is examined more frequently at autopsy.
作者描述了一例68岁男性的尸检病例，该患者在尸检时被诊断出患有四种原发性癌症，包括恶性脑膜瘤、早期食管癌、早期胃癌和肺癌。最近，患有四种和五种原发性癌症的患者数量一直在增加。根据《日本病理尸检病例年报》，在1974年至1989年的16年间共报告了156例。在这个系列中，癌症最常出现在胃、结肠、肺、前列腺、肝脏和食管。然而，仅报告了两例包括恶性脑膜瘤在内的四种和五种原发性癌症病例。由于像前列腺癌这样的隐匿性癌症在尸检时意外被诊断出来，当在尸检时更频繁地检查中枢神经系统时，包括恶性脑膜瘤在内的四种和五种原发性癌症的发病率似乎更高。
