Oyama Ian A, Wakabayashi Mark T, Frattarelli LeighAnn C, Kessel Bruce
Department of Obstetrics and Gynecology and Women's Health, John A. Burns School of Medicine, University of Hawaii, HI, USA.
Am J Obstet Gynecol. 2003 May;188(5):1164-5. doi: 10.1067/mob.2003.290.
This study was undertaken to determine whether administration of local anesthetic reduces pain associated with colposcopically directed cervical biopsies.
Fifty-six patients undergoing colposcopically directed cervical biopsies were randomly selected prospectively to receive a 1% lidocaine injection or no injection before the biopsy procedure. Pain was assessed by using a 10-cm visual analog scale at various points during the procedure. Data were analyzed with the Student t test.
Injection of lidocaine resulted in a reduction in pain scores for cervical biopsies (4.004 to 1.166, P: <.001), endocervical curettage (5.757 to 3.900, P =.0018), and overall procedure scores (4.911 to 3.145, P =.0013).
This pilot study demonstrates that injection of local anesthetic at the site of colposcopically direct cervical biopsies decreases the pain perceived by patients.
本研究旨在确定局部麻醉剂的使用是否能减轻阴道镜引导下宫颈活检相关的疼痛。
前瞻性随机选取56例接受阴道镜引导下宫颈活检的患者，在活检操作前分别接受1%利多卡因注射或不注射。在操作过程中的不同时间点，使用10厘米视觉模拟量表评估疼痛程度。数据采用学生t检验进行分析。
利多卡因注射使宫颈活检的疼痛评分降低（从4.004降至1.166，P<0.001），宫颈管刮除术的疼痛评分降低（从5.757降至3.900，P = 0.0018），总体操作评分降低（从4.911降至3.145，P = 0.0013）。
这项初步研究表明，在阴道镜引导下宫颈活检部位注射局部麻醉剂可减轻患者的疼痛感受。
