Giné E, Rovira M, Real I, Burrel M, Montaña J, Carreras E, Montserrat E
BMT Unit, Hematology Department, Institute of Hematology and Oncology, Postgraduate School of Hematology, Spain.
Bone Marrow Transplant. 2003 May;31(10):923-5. doi: 10.1038/sj.bmt.1703954.
Hemorrhagic cystitis (HC) is a common and sometimes life-threatening complication of hemopoietic cell transplantation (HCT) occurring in 7-52% of transplant recipients. In this setting it is usually either related to the use of cyclophosphamide or to a viral infection (BK, JC viruses and adenovirus type 11). Treatment is based on hyperhydration, platelet and blood-cell transfusions, bladder irrigation and pain management. Where these measures have failed to control HC, numerous therapeutic approaches including surgery have been tried with poor success. We report two HCT patients with severe HC successfully treated with selective embolization of the vesical arteries.
出血性膀胱炎（HC）是造血细胞移植（HCT）常见且有时危及生命的并发症，在7%至52%的移植受者中发生。在这种情况下，它通常与环磷酰胺的使用或病毒感染（BK、JC病毒和11型腺病毒）有关。治疗基于水化、输注血小板和血细胞、膀胱冲洗及疼痛管理。当这些措施未能控制HC时，包括手术在内的多种治疗方法都已尝试，但效果不佳。我们报告了两名严重HC的HCT患者通过选择性膀胱动脉栓塞成功治愈。
