Hughes A J, Schwarer A P, Millar I L
Bone Marrow Transplant Programme, Alfred Hospital, Melbourne, Australia.
Bone Marrow Transplant. 1998 Sep;22(6):585-6. doi: 10.1038/sj.bmt.1701376.
Haemorrhagic cystitis is a common and often debilitating complication of chemotherapy for which treatment is frequently unsatisfactory. With over 80 cases reported of radiation-induced cystitis treated successfully with hyperbaric oxygen, attention is now turning to the treatment of chemotherapeutic agent-induced cystitis. We report a case of haemorrhagic cystitis occurring after autologous peripheral blood stem cell transplantation for multiple myeloma. The patient had received cyclophosphamide and busulfan and had BK and adenoviruria. The haemorrhage was refractory to multiple conventional treatments but resolved after a course of hyperbaric oxygen.
出血性膀胱炎是化疗常见且往往使人衰弱的并发症，其治疗常常不尽人意。已有80多例放射性膀胱炎经高压氧成功治疗的报道，现在人们的注意力正转向化疗药物所致膀胱炎的治疗。我们报告1例多发性骨髓瘤自体外周血干细胞移植后发生出血性膀胱炎的病例。该患者接受了环磷酰胺和白消安治疗，且存在BK病毒尿症和腺病毒尿症。出血对多种传统治疗均无效，但在一个疗程的高压氧治疗后得以缓解。
