Hansen Mark Berner
Department of Gastrointestinal Surgery K, Bispebjerg University Hospital of Copenhagen, Copenhagen NV, Denmark.
Pharmacol Toxicol. 2003 Mar;92(3):105-13. doi: 10.1034/j.1600-0773.2003.t01-1-920301.x.
Major advances have been made in our understanding of the nervous system in the gastrointestinal tract, the enteric nervous system. Because of its importance, neurogastroenterology is being increasingly recognised in clinical pharmacology. The enteric nervous system is a collection of neurones that can function more or less independently of the central nervous system and controls or modulates motility, exocrine and endocrine secretions, microcirculation and immune and inflammatory processes. Increasing knowledge of the physiology, pathophysiology, and pharmacology of the enteric nervous system will provide a basis for creation of new approaches to the treatment of gastrointestinal disorders. This review is part one of three and will describe the organisation and classification of the enteric nervous system.
我们对胃肠道中的神经系统，即肠神经系统的理解取得了重大进展。由于其重要性，神经胃肠病学在临床药理学中越来越受到认可。肠神经系统是一组神经元的集合，其功能或多或少独立于中枢神经系统，并控制或调节蠕动、外分泌和内分泌分泌、微循环以及免疫和炎症过程。对肠神经系统生理学、病理生理学和药理学的了解不断增加，将为创建治疗胃肠道疾病的新方法提供基础。本综述是三篇系列文章中的第一篇，将描述肠神经系统的组织和分类。
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