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职业性头部损伤与后续的胶质瘤

Occupational head injury and subsequent glioma.

作者信息

Magnavita N, Placentino R A, Mei D, Ferraro D, Di Trapani G

机构信息

Institute of Occupational Medicine, Catholic University School of Medicine, Rome, Italy.

出版信息

Neurol Sci. 2003 Apr;24(1):31-3. doi: 10.1007/s100720300018.

DOI:10.1007/s100720300018
PMID:12754654
Abstract

We report the case of a policeman who suffered a severe head injury to the right temporoparietal lobe while driving a police car. Four years later, the patient developed a neoplasm at the precise site of the meningocerebral scar. Histological examination confirmed a glioblastoma multiforme adjacent to the dural scar. Radiological documentation of the absence of tumor at the time of injury, exact localization of the neoplasm in the injured cerebral area, and latency of the cancer supported the hypothesis of a causal relationship with brain trauma. Physicians faced with brain neoplasms in adults should carefully investigate the patient's personal history of head trauma. When a relationship with occupational head injury is probable, reporting of suspect occupational illness is compelling.

摘要

我们报告了一名警察的病例,他在驾驶警车时右侧颞顶叶遭受严重头部损伤。四年后,患者在硬脑膜脑瘢痕的精确部位出现了肿瘤。组织学检查证实为多形性胶质母细胞瘤,毗邻硬脑膜瘢痕。受伤时肿瘤不存在的影像学记录、肿瘤在受伤脑区的精确定位以及癌症的潜伏期支持了与脑外伤存在因果关系的假设。面对成人脑肿瘤的医生应仔细调查患者的头部外伤个人史。当可能与职业性头部损伤有关时,报告可疑职业疾病是必要的。

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Occupational head injury and subsequent glioma.职业性头部损伤与后续的胶质瘤
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The long-term risk of malignant astrocytic tumors after structural brain injury--a nationwide cohort study.结构性脑损伤后恶性星形细胞瘤的长期风险——一项全国性队列研究。
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