Dabak Nevzat, Tomak Yilmaz, Piskin Ahmet, Gulman Birol, Ozcan Hakan
Department of Trauma and Orthopaedic Surgery, Faculty of Medicine, Ondokuz Mayis University, 55139 Kurupelit, Samsun, Turkey.
Int Orthop. 2003;27(4):249-53. doi: 10.1007/s00264-003-0463-8. Epub 2003 May 20.
The objective of this study was to present a simple, convenient, and reliable technique for the application of liquid nitrogen and to evaluate the effectiveness of curettage and cryosurgery. Between 1992 and 2002, 24 patients who had benign aggressive and low-grade malignant bone tumors were treated by curettage and cryosurgery. While cryosurgery was applied by the "direct pour" technique in the first seven patients, it was applied by the "pressurized spraying" technique in the others. Functional results were graded according to Enneking. The mean follow-up was 47 (range 9-131) months. There were no local recurrences. Three patients who underwent the direct pour technique developed partial skin necrosis. The functional results were excellent in 14 patients, good in six, and fair in four. When compared with previous reports on cryosurgery and its application techniques, we detected no tumor recurrence or complications, including soft-tissue injury, infection, and late fracture with liquid nitrogen applied by the pressurized spraying technique.
本研究的目的是介绍一种简单、便捷且可靠的液氮应用技术，并评估刮除术和冷冻手术的有效性。1992年至2002年间，24例患有良性侵袭性和低度恶性骨肿瘤的患者接受了刮除术和冷冻手术治疗。前7例患者采用“直接倾倒”技术进行冷冻手术，其余患者采用“加压喷雾”技术。根据Enneking标准对功能结果进行分级。平均随访时间为47个月（范围9 - 131个月）。无局部复发。采用直接倾倒技术的3例患者出现了部分皮肤坏死。14例患者功能结果为优，6例为良，4例为中。与先前关于冷冻手术及其应用技术的报告相比，我们发现采用加压喷雾技术应用液氮时，未出现肿瘤复发或包括软组织损伤、感染及迟发性骨折在内的并发症。
