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脊柱原发性骨病变:治疗方法选择的综述。

Vertebral Primary Bone Lesions: Review of Management Options.

机构信息

Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL 32601, USA.

出版信息

Curr Oncol. 2023 Mar 4;30(3):3064-3078. doi: 10.3390/curroncol30030232.

Abstract

The assessment and treatment of vertebral primary bone lesions continue to pose a unique yet significant challenge. Indeed, there exists little in the literature in the way of compiling and overviewing the various types of vertebral lesions, which can often have complicated intervention strategies. Given the severe consequences of mismanaged vertebral bone tumors-including the extreme loss of motor function-it is clear that such an overview of spinal lesion care is needed. Thus, in the following paper, we aim to address the assessment of various vertebral primary bone lesions, outlining the relevant nonsurgical and surgical interventional methods. We describe examples of primary benign and malignant tumors, comparing and contrasting their differences. We also highlight emerging treatments and approaches for these tumors, like cryoablation and stereotactic body radiation therapy. Ultimately, we aim to emphasize the need for further guidelines in regard to correlating lesion type with proper therapy, underscoring the innate diversity of vertebral primary bone lesions in the literature.

摘要

椎体原发性骨病变的评估和治疗仍然是一个独特而又重大的挑战。事实上,在文献中,几乎没有对各种类型的椎体病变进行汇编和综述,而这些病变往往具有复杂的干预策略。鉴于椎体骨肿瘤管理不善会导致严重后果,包括运动功能的极度丧失,显然需要对脊柱病变护理进行这样的综述。因此,在下面的论文中,我们旨在探讨各种椎体原发性骨病变的评估,概述相关的非手术和手术介入方法。我们描述了原发性良性和恶性肿瘤的例子,比较和对比了它们的差异。我们还强调了这些肿瘤的新兴治疗方法和途径,如冷冻消融和立体定向体部放射治疗。最终,我们旨在强调需要进一步制定相关指南,将病变类型与适当的治疗方法相联系,强调文献中椎体原发性骨病变的固有多样性。

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