与5β-雄甾烷相关的类固醇对培养的鸡胚盘血红蛋白合成的调节
The regulation of haemoglobin synthesis in cultured chick blastoderms by steroids related to 5beta-androstane.
作者信息
Irving R A, Mainwaring I P, Spooner P M
出版信息
Biochem J. 1976 Jan 15;154(1):81-93. doi: 10.1042/bj1540081.
Abstract
- After 24h of incubation, the blastoderm may be dissected from the early developing chick embryo and successfully maintained under conditions of organ culture in vitro. 2. Low concentrations of steroids related to 5beta-androstane stimulate the synthesis of foetal haemoglobins, types E and P, in a highly steroid- and tissue-specific manner.
摘要
- 孵育24小时后，可从早期发育的鸡胚中分离出胚盘，并在体外器官培养条件下成功维持其存活。2. 低浓度的与5β-雄甾烷相关的类固醇以高度类固醇和组织特异性的方式刺激E型和P型胎儿血红蛋白的合成。
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